Abstract A diverse array of theoretical models DNA-based self-assembling systems have been proposed and studied. Beyond providing simplified abstractions in which to develop designs for molecular implementation, these provide platforms explore powers limitations “in the limit” compare relative strengths weaknesses components varying capabilities constraints. As often intentionally overlook many...

The use of DNA nanotechnology is rapidly growing due to the unprecedented programmability geometric, mechanical, and dynamic properties. This technology has led an impressive library nanoscale structures devices that are useful across physics, chemistry, engineering. A challenge for materials researchers engineers reliably expand larger scales, much like natural biomolecular assemble components...

DNA nanotechnology takes advantage of the predictability of DNA interactions to build complex DNA-based functional nanoscale structures. However, when DNA functional and responsive units that are based on non-canonical DNA interactions are employed it becomes quite challenging to predict, understand and control their thermodynamics. In response to this limitation, here we demonstrate the use of...

DNA base-pairing is the central interaction in DNA assembly. However, this simple four-letter (A-T and G-C) language makes it difficult to create complex structures without using a large number of DNA strands of different sequences. Inspired by protein folding, we introduce hydrophobic interactions to expand the assembly language of DNA nanotechnology. To achieve this, DNA cages of different ge...

DNA, apart from being a natural biological information carrier, has also been recognized as a useful building material in the field of nanotechnology. Its miniature scale, geometric properties, and molecular recognition capacity make DNA an appealing candidate for the construction of novel nanomaterials. Here we summarize the latest developments and describe the challenges and emerging applicat...

Nanotechnology is one of the most important tools in modern agriculture, and agri-food nanotechnology is anticipated to become a driving economic force in the near future. Agri-food themes focus on sustainability and protection of agriculturally produced foods, including crops for human consumption and animal feeding. Nanotechnology provides new agrochemical agents and new delivery mechanisms t...

Nanotechnology has changed our lives dramatically and influenced every sector of the research, engineering and also business community. Nanotechnology is a rapidly growing science of producing and utilizing nano-sized particles, that measure in nanometer. In other words, nanotechnology is the art of characterizing, manipulating and organizing matter systemically, at the nanometer scale, which h...

Nanotechnology has changed our lives dramatically and influenced every sector of the research, engineering and also business community. Nanotechnology is a rapidly growing science of producing and utilizing nano-sized particles, that measure in nanometer. In other words, nanotechnology is the art of characterizing, manipulating and organizing matter systemically, at the nanometer scale, which h...

The structural reorganization of nanoscale DNA architectures is a fundamental aspect in dynamic DNA nanotechnology. Commonly, DNA nanoarchitectures are reorganized by means of toehold-expanded DNA sequences in a strand exchange process. Here we describe an unprecedented, toehold-free switching process that relies on pseudo-complementary peptide nucleic acid (pcPNA) by using a mechanism that inv...