نتایج جستجو برای: double blind
تعداد نتایج: 276773 فیلتر نتایج به سال:
The objective of this paper is to develop statistical methodology for non-inferiority hypotheses to censored, exponentially distributed time to event endpoints. Motivated by a recent clinical trial in depression, we consider a gold standard design where a test group is compared with an active reference and with a placebo group. The test problem is formulated in terms of a retention of effect hy...
OBJECTIVES To investigate the efficacy of a second subcutaneous dose of 6 mg sumatriptan in the treatment of recurrence of headache after successful treatment of a migraine attack with an initial 6 mg dose. METHODS In a prospective, randomised, placebo controlled, double blind, parallel group study, 803 patients were treated for one to three migraine attacks with severe or moderate headache w...
Double-blind review relies on the authors’ ability and willingness to effectively anonymize their submissions. We explore anonymization effectiveness at ASE 2016, OOPSLA 2016, and PLDI 2016 by asking reviewers if they can guess author identities. We find that 74%–90% of reviews contain no correct guess and that reviewers who self-identify as experts on a paper’s topic are more likely to attempt...
To investigate the effects of supplemental oxygen on cardiac rhythm during gastroscopy, 103 patients aged over 60 were randomised to receive either supplemental oxygen or air at 2 litres/minute during the procedure. Pulse rate, blood pressure, oxygen saturation, and a Holter cardiac trace were monitored before, during, and for one hour after the gastroscopy. A wide range of electrocardiographic...
Thirty melancholic patients participated in a double blind trial comparing efficacy of modified bilateral sinewave ECT given twice or thrice weekly. Seizure was monitored on a single channel EEG tracing. All patients received ECTs in the first two weeks of the four week study period. Seizure duration estimate from EEG tracings available for 22 patients (10 patients of thrice weekly group) on al...
BACKGROUND The Phase 2b double-blinded, randomized Phambili/HVTN 503 trial evaluated safety and efficacy of the MRK Ad5 gag/pol/nef subtype B HIV-1 preventive vaccine vs placebo in sexually active HIV-1 seronegative participants in South Africa. Enrollment and vaccinations stopped and participants were unblinded but continued follow-up when the Step study evaluating the same vaccine in the Amer...
Double pylorus (DP) is a rare condition characterized by the presence of two openings from the gastric antrum to the duodenal bulb, which may be congenital or acquired. Herein, we describe a case of DP in a cirrhotic patient.
BACKGROUND To investigate the controlling efficacy of ondasetron and haloperidol in regard to the postcardiotomy delirium. METHODS We included in this prospective, randomized, double-blinded study 80 patients who developed delirium after heart surgery with the application of heart lung-machine. The patients were divided into two, equally-sized groups, which on detection of delirium received o...
Depressive mood is a common accompaniment of schizophrenia. The present study was taken up with the aim to study the effect of imipramine on depressivse symptoms of schizophrenia. Eighteen patients of schizophrenia with depressive symptoms were studied under a double blind controlled design with a chlorpromazine-imipramine and a chlorpromazine-placebo group. Both the groups showed significant i...
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