Introduction: Parkinson’s Disease (PD) is a progressive neurodegenerative disease. Increasing evidence shows that physical exercise is beneficial for motor and non-motor symptoms of PD, and animal models suggest that it may help slow progression of disease. Methods: Using a randomized delayed-start design, 31 patients were randomized to an early start group (ESG) or a delayed start group (DSG) ...

Plant density was varied with P, Ca, Mg, and KNO3 in a multifactor experiment to improve Curcuma longa L. micropropagation, biomass and microrhizome development in fed-batch liquid culture. The experiment had two paired D-optimal designs, testing sucrose fed-batch and nutrient sucrose fed-batch techniques. When sucrose became depleted, volume was restored to 5% m/v sucrose in 200 ml of modified...

Aim. Analysis of physiological and biochemical characteristics genetically modified wheat with partially suppressed activity the proline dehydrogenase gene. Methods. Determination (PDH) activity, free L-proline (Pro); carbohydrate content (sucrose fructose). Results. It was established that under conditions water deficit in plants integrated elements forming double-stranded RNA suppressor pdh g...

Due to persistent difficulties experienced under routine conditions of analysis, considerable attention has been given in this laboratory to determining a satisfactory alternative procedure to the double polarisation method for sucrose in final molasses. For some time the Eynon~Lane technique has been employed for measuring the reducing sugars and re. ducing sugars plus inverted sucrose in fina...

OBJECTIVES There is no consensus on the most effective pain management for neonatal circumcision. We sought to compare different modalities. METHODS This is a double-blinded randomized controlled trial comparing 3 combination analgesics used during circumcision (EMLA + sucrose; EMLA + sucrose + dorsal penile nerve block [DPNB]; EMLA + sucrose + ring block [RB]) with the traditional topical an...

Compared with recirculation and injection modes, once-through direct steam generation (DSG) parabolic troughs are simpler to construct and require the lowest investment. However, the heat transfer fluid (HTF) in once-through DSG parabolic trough systems has the most complicated dynamic behavior, particularly during periods of moving shadows caused by small clouds and jet contrails. In this pape...

Development of human antimouse antibody (HAMA) is a major limiting factor in the application of murine mAb for clinical use. A novel immunomodulatory drug, deoxyspergualin (DSG), has shown potential to suppress antimouse antibody response in preclinical model systems. We conducted a Phase I trial to determine the effect of DSG on HAMA response to murine mAb L6 administered to patients with adva...