We describe an experimentation environment that enables large-scale numerical simulations of neural microphysiology to be fed back onto living neurons in-vitro via dynamic wholecell patch clamping – in effect making living neurons and simulated neurons part of the same neural circuit. Owing to high computational demands, the experimental testbed will be dispersed over a local area network compr...

We simulate a computer system by modeling its users as individuals who have separate needs for resources like processes and login time. During the simulations the users make decisions with probabilities which depends on the time of day and on the character of the user. This makes us able to reproduce the large scale behavior measured at real computer systems as well as predicting the behavior o...

A number of approaches have been recently proposed by different vendors for the next generation Internet router architectures, capable of processing millions of packets per second. Most of this processing speed stems from employing latest high-performance network processor or multiprocessors as the forwarding engine of the router. However, all these improvements have been proposed without any d...

| We illustrate the sensitivity of trace driven simulation results to the completeness of the input trace data. This is done by comparing cache simulation results obtained using traces similar to many found in the published literature with those obtained using a hardware monitor which we have developed. Cache miss rates from single process traces without operating system references are shown to...

Reputation and trust-based models have gained popularity recently because they have been shown to be promising in the area of trust management. Despite this fact, building reliable systems still remains a challenge. Proposed models focus on historical and online information to determine the reputation of domain members. However, the dynamic nature of reputation and trust requires an equally dyn...

In our research, the simulation model driven engineering for manufacturing cell (SMDE-MC) is proposed. The purposes of SMDE-MC are to support the manufacturing engineering processes based on the simulation model and to extend the range of control applications and simulation applications using the PC based control. SMDE-MC provides the simulation model which controls and monitors the manufacturi...

Microscopic models are state of the art for computer simulation of pedestrian dynamics. The modeling of the individual movement of pedestrians is used to design a description of macroscopic pedestrian flow which allows e.g. the evaluation of escape routes, the design of pedestrian facilities and the study of more theoretical questions. For a first overview see [1–3]. One primary test, whether a...

Evaluating landing technique using a computer simulation model of a gymnast and landing mat could be a useful tool when attempting to assess injury risk. The aims of this study were: (1) to investigate whether a subject-specific torque-driven or a subject-specific muscle-driven model of a gymnast is better at matching experimental ground reaction forces and kinematics during gymnastics landings...

Expansion of space, rather than the progress of time, drives many developmental processes in plants. Metric-driven grammars provide a formal method for specifying and simulating such processes. We illustrate their operation using cell division patterns, phyllotactic patterns, and several aspects of leaf development.

This paper reports progress on gyrokinetic particle simulation of turbulence in fusion plasmas including: (1) Electron transport driven by short wavelength trapped electron mode turbulence; (2) Convergence studies and physics progress in long time simulation of electron temperature gradient turbulence; (3) Electromagnetic simulation of global magnetohydrodynamic modes and finite-β stabilization...