enterococci, as the major cause of nosocomial infections, have been shown to have an increase in drug resistance during the past two decades. theentrococcalemergence of vancomycin-resistant is very important nowadays. the purpose of this study was to determine the drug sensitivity of enterococcus faecalis and enterococcus faecium species against vancomycin, tetracycline, gentamicin, erythromyci...

conclusions the results of this study indicated that a decrease in oprd gene expression is an important mechanism of resistance in carbapenem resistant pseudomonas aeruginosa isolated from severe burn patients with secondary infection. results our study showed that 94.2% of the isolates were resistant to imipenem, 99.5% to meropenem, and all were resistant to ertapenem. the oprd gene expression...

background: campylobacter infections may lead to serious conditions, including septicemia or other invasive forms of the disease, which require rapid and accurate laboratory diagnosis and subsequently appropriate antimicrobial therapy. the aim of this study was to compare the species distribution and antimicrobial susceptibility pattern of campylobacter spp. strains isolated from patients and f...

of gene of interest. Most studies have employed drug resistance genes, such as the neomycin resistance gene (neo), to eliminate unwanted, untransfected cells after transfection. In such cases, the drug resistance genes are integrated into host chromosomes upon transfection so that they synthesize proteins capable of degrading drugs present in medium. However, this method often causes unwanted b...

Transient receptor potential cation channel, subfamily C, member 1 (TRPC1) participates in many physiological functions but has also been implicated in cancer development. However, little is known about the role of TRPC1 in ovarian cancer (OC), including the drug resistance of these tumors. In the present study, a significant and consistent downregulation of TRPC1 in drug-resistant OC tissues/c...

conclusions in this study, like previous researches, e. coli was the most common pathogen. our results suggested a high rate of antibiotic resistance to common antibiotics for treatment of uti. because of the high resistance to cephalexin, cefotaxime and co-trimoxazole, their use is not recommended for treatment of utis. imipenem and vancomycin were the most active drugs against e. coli and sta...