Drug should be used appropriately, safely and only when needed 50% or more of drug expenditure may be wasted through irrational prescribing, dispensing and patient use of drugs. Drug use evaluation is one of the useful methods to evaluate the rational use of drug in health institution and has performance of improved method that focus evaluation and improving medication use process with the goal...

The present investigation was aimed at developing a novel colon targeted system of lornoxicam based on the use of a combination of pH dependent system (to prevent the premature release of drug in the upper GIT) and enzymatically degradation system (to ensure the specificity of drug release in the colon). The drug loaded guar gum microspheres prepared by emulsification cross-linking method were ...

inappropriate use of drugs is a widespread problem with serious consequences such as increased adverse drug reaction and antimicrobial resistance. proper interventions would have important financial and public health benefits. several studies have been performed about rational drug use (rud) in iran. to provide a picture of researches were done about rud and highlight the existing gaps in pract...

BACKGROUND Reports of chronic pain and associated opioid use, abuse, and fatalities continue to increase at an alarming rate, not only in the United States but also across the globe. In light of the many resultant fatalities, multiple authors and authorities have cautioned against the excessive use of opioids. Consequently, the Food and Drug Administration, Drug Enforcement Administration, and ...

CONTEXT Cost-sharing in US prescription drug coverage plans for elderly persons varies widely. Evaluation of prescription drug use among elderly persons by type of health insurance could provide useful information for designing a Medicare drug program. OBJECTIVE To determine use of effective cardiovascular drugs among elderly persons with coronary heart disease (CHD) by type of health insuran...