The objective of the present study was to determine if patients with COPD who were taking Theo-Dur bid or tid (total dose 400 to 900 mg per day) could be safely switched to Uni-Dur, 800 mg given qd at bedtime. Twenty-eight patients were enrolled in the study, and 23 completed the study. The mean daily dose of theophylline prior to the study was 828 mg, while the mean dose after three weeks of U...

INTRODUCTION Review of adverse outcomes is an essential element of healthcare governance. For each operational death, the post-mortem is attended by a member of Academic Department of Military Emergency Medicine and the case is assessed by a Mortality Peer Review Panel comprised of Defence Professors and other clinical and technical experts. METHODS A search was conducted of the Joint Theatre...

OBJECTIVES Overcrowding in the emergency department (ED) is common in the UK as in other countries worldwide. Computer simulation is one approach used for understanding the causes of ED overcrowding and assessing the likely impact of changes to the delivery of emergency care. However, little is known about the usefulness of computer simulation for analysis of ED patient flow. We undertook a sys...

A Swr-Edwards Silsstic hd-valve prosthesis was inserted in 100 seriously d l M e d patients with isolated aortic (55 case) or m i l d (45 caws) valve dbease. The follow-up study for periods of Urree years or more resulted in the following points. The o v e d mortslity rate reached 35 percent in both groups. but the operative risks were t h m times lea in the mrtic thno in the m i i d group. Thr...

stalk being 10–13 residues shorter than that of the 45-residue CD8␣ stalk (Kern et al., 1998). The presence of numerous proline residues plus O-glycans in both stalks indicate that they assume an extended conformation (Classon et al., 1992). CD8 glycan adducts change dur

Water is the only constituent of the amphibian embryo that is taken u p from the environment in appreciable quantities dur ing the course of development, and at hatching it occupies nearly three t imes as m u c h space in the embryo as all the other consti tuents combined. I n spite of its small molecular size, however, and its ability to diffuse freely throughout the embryo, water is not unifo...

Anthropogenic activities have increased nitrogen (N) deposition by threefold to fivefold over the last century, which may considerably affect soil respiration (Rs). Although numerous individual studies and a few meta-analyses have been conducted, it remains controversial as to how N addition affects Rs and its components [i.e., autotrophic (Ra) and heterotrophic respiration (Rh)]. To reconcile ...