The effect of P-glycoprotein (Pgp) and/or CYP3A on the disposition of xenobiotics has been extensively investigated and is often of interest during drug discovery lead optimization. We have previously described a monkey pharmacokinetic screen to rapidly estimate absorption and first-pass extraction. In the present work, this monkey screen has been expanded to include an assessment of Pgp/CYP3A ...

OBJECTIVE To identify factors associated with total sedentary time and screen time in children aged 9-11 years. METHODS For seven consecutive days, 328 children (51.5% boys) used accelerometers to monitor total sedentary time. Screen time was calculated by the self-reporting method. Individual, family, family environment, and school environment questionnaires were filled out. Body composition...

PURPOSE To determine whether organic electroluminescence (OLED) screens can be used as visual stimulators to elicit pattern-reversal visual evoked potentials (p-VEPs). METHOD Checkerboard patterns were generated on a conventional cathode-ray tube (S710, Compaq Computer Co., USA) screen and on an OLED (17 inches, 320 × 230 mm, PVM-1741, Sony, Tokyo, Japan) screen. The time course of the lumina...

The family plays a central role in the development of health-related behaviors among youth. The objective of this study was to determine whether non-traditional parental structure and shared custody arrangements predict how much time youth spend watching television, using a computer recreationally, and playing video games. Participants were a nationally representative sample of Canadian youth (...

Digital camera has been adopted for the booster, storage ring and transport-line diagnostic recently at the Taiwan Light Source. The system provides low image distortion transmission over long distance. The system is integrated with control system. Each screen monitor equip with a digital camera. These screen monitors are used for beam profile measurement and help injection condition optimizati...

A learning environment having more than one screen enables users to display and compare various sources of learning information with two adjacent screens illustrating the development of interrelated concepts and showing their relationships. This proposed technique could provide higher quality resources for learners by addressing physical and psychological factors. However, attention is a limite...

L-Band SAR, like that on the JAXA’s ALOS PALSAR instrument, is much more susceptible to ionospheric effects than other space based SAR missions, mainly operating in C-band or X-Band. While single-band attenuation of instruments such as the single-polarization JERS-1 SAR instrument certainly occurred, it was rarely noted. With the advent of fulland dual-polarization (full-pol and dual-pol) instr...

[Purpose] This study compared the orbicularis oculi muscle activity during computer work with single and dual monitors. [Subjects] Ten computer workers 22-27 years of age were included in this study. [Methods] Subjects performed computer work with single or dual monitors, and the activity of the right orbicularis oculi muscle was measured with a MP150 system. [Results] The muscle activity of th...

Web TV is making a comeback, as users increasingly co-consume TV related web content on their companion devices (tablets and smartphones) in sync with TV watching. In this ‘dual screen’ experience, users download and invoke TV apps on their companion devices to personalize their Superbowl or American Idol TV experience with a web counterpart. Unfortunately, the added effort in continually findi...

Formulation for calculating forward propagation and reflection in a 3D elastic structure based on the complex-screen method is given in this paper. The calculation of reflections is formulated based on the local Born approximation. When using a small angle approximation, the backscattering operator reduces to a screen operator which is similar to the forward screen propagator. Combining the for...