Classification Invasive ductal carcinoma is a heterogeneous group with many different subtypes, some of them extremely rare. Each of these variants is associated with another pathological presentation and with a different prognosis compared to invasive ductal carcinoma of no special type (NST). As shown in Figure 1, some of the most important subclassifications are: Medullary carcinoma: younger...

The authors retrospectively examined the contralateral prophylactic mastectomy (CPM) rate among 100 women with ductal carcinoma in situ who are BRCA negative. Of 100 women with ductal carcinoma in situ, 31 elected contralateral prophylactic mastectomy (CPM). Factors associated with increased likelihood of undergoing contralateral prophylactic mastectomy (CPM) among this cohort were: family hist...

Infiltrating ductal carcinoma arising in a fibroadenoma is a rare incidental finding. Incidence is 0.0020.0125%. Women having proliferative disease without atypia have a twofold elevation in their risk for subsequent invasive breast cancer. We here present a case report in a 38 year female having fibroadenoma, intraductal papilloma and fibocystic disease of breast who subsequently developed inv...

Invasive ductal carcinoma NOS, or no special type, is the most common type of breast cancer representing 65% to 75% of mammary carcinomas (1,2). Depending on the size of the lesion, size of the breast, and proximity of the lesion to the skin, patients can present with a hard, fixed, palpable mass that may cause skin thickening and retraction (Fig. 8.1). If the cancer is in the subareolar area, ...

Background: The nuclear grading of ductal carcinoma in situ (DCIS) affects its clinical risk. aim this study was to investigate the possibility predicting DCIS, by magnetic resonance imaging (MRI)-based radiomics features. And develop a nomogram combining features and MRI semantic explore potential role radiomic assessment DCIS grading.

Prostatic ductal adenocarcinomas may arise either in large primary periurethral prostatic ducts or in the peripheral prostatic ducts. Ductal adenocarcinomas are composed of tall columnar cells arranged in cribriform, papillary, solid, single glands, and PIN-like patterns. Other than the prostatic intraepithelial neoplasia (PIN)-like ductal pattern, which behaves like Gleason pattern 3, ductal a...

Occurrence of multiple primary malignant tumors is very uncommon .Co occuring can be synchronous or non synchronous.Tumors presenting within a period less than equal to 6 months are called and if they occur after termed as metachronous. Synchronous malignancies rarer For defining both the should show criteria malignancy, possibility metastasis must have been ruled out pathologically distinct. B...

High-grade ductal carcinoma in situ is incredibly rare in male patients. The prognosis for ductal carcinoma in situ (DCIS) in a male patient is the same as it would be for a female with the same stage disease; therefore, early recognition and diagnosis are of the utmost importance. We present a case of a male with unilateral invasive ductal carcinoma who was diagnosed with DCIS in the contralat...

Our goal was to assess the value of surgical excision of benign papillomas of the breast diagnosed on percutaneous core biopsy by determining the frequency of upgrade to malignancies and high risk lesions on a final surgical pathology. We reviewed 67 patients who had biopsies yielding benign papilloma and underwent subsequent surgical excision. Surgical pathology of the excised lesions was comp...

The mRNA encoding the calcium-binding protein psoriasin was identified as being more highly expressed in the in situ versus the invasive component of the same breast tumor. Reverse transcription-PCR analysis of total RNA extracted from three independent cases of ductal carcinoma in situ of the comedo type and three cases of high-grade invasive ductal carcinoma revealed a detectable level of pso...