Background: Ductal carcinoma in situ (DCIS) is detected more often since the advent of mammography. A standardized pathologic staging and grading system does not exist, but nuclear grade is assuming greater importance. The history of DCIS is long, and its treatment is a controversial issue in breast cancer today. Methods: Data have been reviewed regarding the role of HER-2 expression as a progn...

Ductal carcinoma in situ (DCIS) is a heterogeneous disease in both its biology and clinical course. In the past, recurrence rates after breast-conserving surgery have been as high as 30% after 10 years. The introduction of mammography screening and advances in imaging have led to an increase in the detection of DCIS. The focus of this review is on the role of radiotherapy in the multidisciplina...

BACKGROUND Breast-specific gamma imaging (BSGI) is a functional imaging modality that has comparable sensitivity but superior specificity compared with magnetic resonance imaging, yielding fewer false-positive results and thereby improving clinical management of the newly diagnosed breast cancer patient. METHODS A retrospective review was performed from 2 community-based breast imaging center...

The growth of avascular tumors has been studied by many authors. In this paper we study a special kind of cancer, ductal carcinoma in situ (DCIS) in order to investigate possible procedures to connect free boundary model of DCIS with clinical data. This paper is to present some results of our research on mathematical modeling, analysis, and numerical simulations of ductal carcinoma in situ. In ...

A case is described in which calcium oxalate (Weddellite) crystals were identified in an area of ductal carcinoma in situ of the breast. Seventy other cases were examined but no evidence of Weddellite was detected. This is evidently a rare phenomenon in carcinoma in situ. (J Clin Pathol 1999;52:145–146)

Background: The nuclear grading of ductal carcinoma in situ (DCIS) affects its clinical risk. aim this study was to investigate the possibility predicting DCIS, by magnetic resonance imaging (MRI)-based radiomics features. And develop a nomogram combining features and MRI semantic explore potential role radiomic assessment DCIS grading.

Collagenous spherulosis (CS) is a rare benign lesion which typically presents as an incidental microscopic finding accompanying other breast lesions. Pathologists who are not familiar with this entity occasionally misdiagnose CS as adenoid cystic carcinoma (ACC), cribriform ductal carcinoma in situ (C-DCIS), or atypical intraductal hyperplasia (AIH), especially when it presents as a mass. It is...

BACKGROUND Screening for invasive cancer has led to a marked increase in the detection of ductal carcinoma in situ (DCIS). DCIS is, if appropriately managed, a low-risk disease which has a small chance of impacting on patient life expectancy. However, despite significant advances in prognostic marker development in invasive breast cancer, there are no validated diagnostic assays to inform treat...