Coeliac disease (CD) is a permanent inflammatory of the small intestine characterized by destruction mucous membrane this intestinal tract. represents most frequent food intolerance and affects about 1% population, but it severely underdiagnosed. Currently available guidelines require CD-specific serology atrophic histology in duodenal biopsy samples to diagnose CD adults. In paediatric CD, rec...

BACKGROUND Helicobacter pylori is implicated as the causative agent for most duodenal and gastric ulcers. Invasive (endoscopy and biopsy) and noninvasive (serology, breath test) methods are currently available for definitive diagnosis of infectious peptic ulcer disease. METHODS Twenty-six patients with chronic gastritis symptoms underwent upper endoscopy, biopsy, rapid urease test, and [14C]u...

Nehme F, Nassif I. BMJ Case Rep 2017. doi:10.1136/bcr-2017-220997 Description A 72-year-old woman presented with a 1-week history of fatigue, weight loss and painless jaundice. Liver chemistries confirmed cholestasis with hyperbilirubinaemia of 25.6 mg/dL. An abdominal CT scan revealed multifocal liver lesions and dilation of intrahepatic and extrahepatic bile ducts. On endoscopic retrograde ch...

The synthesis of gastric and duodenal mucosal prostaglandin E2, prostaglandin I2, and thromboxane B2 during a 60 minute incubation of biopsy specimens, the degree of endoscopic and histological damage, and the anti-inflammatory response were all studied after a four week, double blind study of therapeutic doses of two non-steroidal anti-inflammatory drugs, naproxen and etodolac, received by 27 ...

A 66-year-old man presented with fatigue and acute upper gastrointestinal bleeding (hemoglobin 92g/L). He had melena but no signs of hematemesis. Upper gastrointestinal endoscopy revealed a 35×15-mm large polypoid lesion with multiple ulcerations in the second part of the duodenum (●" Fig.1). No biopsy samples were taken due to the risk of bleeding. The diagnosis was unclear and the patient und...

BACKGROUND Early gastric cancers with duodenal invasion are rare, and no previous case of multiple early gastric cancer, one invading the duodenal bulb, has been reported. CASE PRESENTATION A 79-year-old woman was investigated for upper abdominal discomfort. Endoscopic examination revealed an irregular nodulated lesion in the antrum area, and a reddish aggregated-type semi-circumferential nod...

OBJECTIVES The pathophysiology of functional dyspepsia (FD) is not fully understood. Impaired duodenal mucosal integrity characterized by increased mucosal permeability and/or low-grade inflammation was reported as potentially important etiologies. We aimed to determine the utility of a recently developed simple catheterization method to measure mucosal admittance (MA), the inverse of mucosal i...

PURPOSE Chronic Gastritis is the most common manifestation of infection with Helicobacter pylori. Changes in the gastric mucosa have tendency to progress towards mucosal atrophy, most likely in patients with gastric ulcer. We have explored the frequency of the presence of atrophic gastritis in patients with gastric and duodenal ulcers. MATERIAL AND METHOD We included 175 patients in a prospec...

Candida infection in the small intestine is uncommon. We report an unusual case of duodenal candidiasis that presented as chronic diarrhea in a patient who had previously undergone kidney transplantation. A 60-year-old man presented with profuse watery diarrhea that had lasted 6 months 13 years after kidney transplantation. Upper gastrointestinal endoscopy results indicated candidiasis within t...