objective:more similarity to in vivo medium may help to increase the proliferation and differentiation of cells at in vitro condition. the present study has investigated the effect of a dynamic mediumand nano hydroxyapatite (nha) presence on proliferation and differentiation of mesenchymal stem cells (mscs) to bone cells using electrospun polycaprolactone (pcl) scaffolds. methods: we prepared p...

Software agents representing supply chain partners make it possible to automate supply chain management and particularly can address the challenging problem of automating the process of dynamic supply chain formation. This paper puts forward an extended contract net mechanism for dynamic supply chain formation and applies it to China petroleum supply chain management, which is characterized by ...

in any supply chain, distribution planning of products is of great importance to managers. with effective and flexible distribution planning, mangers can increase the efficiency of time, place, and delivery utility of whole supply chain. in this paper, inventory routing problem (irp) is applied to distribution planning of perishable products in a supply chain. the studied supply chain is compos...

a facility layout problem is concerned with determining the best position of departments, cells, or machines on the plant. an efficient layout contributes to the overall efficiency of operations. it’s been proved that, when system characteristics change, it can cause a significant increase in material handling cost. consequently, the efficiency of the current layout decreases or is lost and it ...

this paper is in search of designing the cellular manufacturing systems (cmss) under dynamic and flexible environment. cm is proper for small-to-medium lot production environment that helps the companies to produce variable kind of productions with at least scraps. the most important benefits of cm are decline in material handling, reduction in work-in-process, reduction in set-up time, increme...

In this article we address the problem of determining how a structured formation of autonomous undistinguishable agents can be reorganized into another, eventually non-rigid, formation based on changes in the environment, perhaps unforeseeable. The methodology can also be used to correctly position the agents into a particular formation from an initial set of random locations. Given the informa...