Despite standard clinical definitions and availability of diagnostic tests for precocious puberty, an intensive and structured investigation is needed in order to diagnose the aetiology in particular cases. A 4-year-old, phenotypically female child was referred to paediatric endocrinology consultation for premature pubarche and thelarche. There was an acceleration of growth velocity with high l...

Torsion of the ovary is uncommon in childhood and usually occurs as a complication of ovarian tumour (Higgins, 1950). Such tumours are rare in this age group (Fraser, 1926) and it was previously thought that most of them were malignant (Lyttle, 1940). Lanman, writing in 1929, could report only five cases among 12,260 children seen in the surgical service of the Children's Hospital at Boston, Ma...

Case Report. Child S.L: 8 years old, was admitted to the Shaab hospital on the 8th. January, 1973 with symptoms of abdominal enlargement noticed a month ago. She came from Nuba Mountains and resident in Omdurman. Although it was difficult to communicate, we could get that there was no pain, no disturbance of bowel habit, 110 problem in micturition and no loss in weight. Appetite was good. She w...

A four-year old, 26.5 kg, Boxer bitch was presented to the Department of Reproduction in the Clinic of Dogs and Cats with a six month history of vulvar swelling and vaginal discharge. General gynaecological examination showed an extremely swollen, oedematous and tough-elastic highly irritable vulva. A vaginal smear revealed the presence of superficial cells and red blood cells. After repeated u...

Gonadoblastomas are known to develop in dysgenetic gonads, especially so, if Y chromosome material is present. A 20-years-old girl who noticed breast development since the age of 12 years presented with primary amenorhoea, distension of lower abdomen and intermittent pain for two months. She had breakthrough bleeding with six months of estrogen replacement. Tanner breast stage was five and pubi...