نتایج جستجو برای: edcs

تعداد نتایج: 732  

Journal: :Molecular medicine reports 2012
Nam-Hee Kang Kyung-A Hwang Tae-Hee Kim Sang-Hwan Hyun Eui-Bae Jeung Kyung-Chul Choi

Resveratrol (trans-3,4',5-trihydroxystilbene; RES), a phytoestrogen, exists in grape skin and red wine. Endocrine disrupting chemicals (EDCs) appear to promote the development and progression of estrogen-dependent cancers. In this study, we evaluated the inhibitory effect of RES on the cell proliferation induced by various EDCs in BG-1 ovarian cancer cells. Various EDCs, such as bisphenol A (BP...

Journal: :Brain Injury 2021

Objective: To establish the current knowledge of sport-related concussion (SRC) management clinicians in emergency departments North West England. Methods: A cross-sectional, multi-centre study design was used and included department (EDCs) across 15 centres 22-question survey issued with questions focused on 5th International Conference Concussion Consensus Statement. Absolute percentages were...

Journal: :Lab on a chip 2007
Pampa Dutta Kasey Hill Panos G Datskos Michael J Sepaniak

A nanomechanical transducer is developed to detect and screen endocrine disrupting chemicals (EDCs) combining fluidic sample injection and delivery with bioreceptor protein functionalized microcantilevers (MCs). The adverse affects of EDCs on the endocrine system of humans, livestock, and wildlife provides strong motivation for advances in analytical detection and monitoring techniques. The com...

2014
Laura N Vandenberg Wade V Welshons Frederick S vom Saal Pierre-Louis Toutain John Peterson Myers

For decades, hazard assessments for environmental chemicals have used intra-gastric gavage to assess the effects of 'oral' exposures. It is now widely used--and in some cases required--by US federal agencies to assess potential toxicity of endocrine disrupting chemicals (EDCs). In this review we enumerate several reasons why gavage is not appropriate for the assessment of EDCs using bisphenol A...

Journal: :Arquivos brasileiros de endocrinologia e metabologia 2014
Elaine Maria Frade Costa Poli Mara Spritzer Alexandre Hohl Tânia A S S Bachega

Environmental agencies have identified a growing number of environmental contaminants that have endocrine disrupting activity, and these can become a major public health problem. It is suggested that endocrine disruptors could account for the higher-than-expected increase in the prevalence of some non-communicable diseases, such as obesity, diabetes, thyroid diseases, and some cancers. Several ...

Journal: :Chemosphere 2006
Rebecca A Trenholm Brett J Vanderford Janie C Holady David J Rexing Shane A Snyder

Endocrine disrupting compounds (EDCs) and pharmaceuticals and personal care products (PPCPs) have been globally detected in impacted natural waters. The detection of trace quantities of EDCs and PPCPs in the environment is of great concern since some of these compounds have known physiological responses at low concentrations. EDCs can have a wide range of polarities, acidic and basic moieties, ...

2007
In-Jeoung Baek Jung-Min Yon Se-Ra Lee Yan Jin Mi-Ra Kim Byeongwoo Ahn Jin Tae Hong Young-Kug Choo Beom Jun Lee Young Won Yun Sang-Yoon Nam

Phospholipid hydroperoxide glutathione peroxidase (PHGPx), an antioxidative selenoprotein, is modulated by estrogen in the testis and oviduct. To examine whether potential endocrine disrupting chemicals (EDCs) affect the microenvironment of the testes, the expression patterns of PHGPx mRNA and histological changes were analyzed in 5-week-old Sprague-Dawley male rats exposed to several EDCs such...

Journal: :European journal of endocrinology 2012
Fang Deng Fang-biao Tao De-yun Liu Yuan-yuan Xu Jia-hu Hao Ying Sun Pu-yu Su

OBJECTIVE The incidence of idiopathic precocious puberty (IPP) might have an increasing trend. But the causes and risk factors of IPP are unknown. The objective of our study is to evaluate the effects of growth environments and two environmental endocrine disruptors (EDCs), zearalenone (ZEA), and 1,1-dichloro-2,2,bisethylene (p,p'-DDE), on patients with IPP. DESIGN Case-control study. METHO...

Journal: :Endocrine-related cancer 2014
Kevin C Knower Sarah Q To Yuet-Kin Leung Shuk-Mei Ho Colin D Clyne

The heritable component of breast cancer accounts for only a small proportion of total incidences. Environmental and lifestyle factors are therefore considered to among the major influencing components increasing breast cancer risk. Endocrine-disrupting chemicals (EDCs) are ubiquitous in the environment. The estrogenic property of EDCs has thus shown many associations between ongoing exposures ...

Journal: :Water research 2008
C Li X Z Li N Graham N Y Gao

The aqueous reactivity of five prominent endocrine disrupting chemicals (EDCs) with potassium ferrate has been studied. The degradation kinetics and reaction pathways for bisphenol A (BPA) have been considered in detail, and the reaction rate constants for 17alpha-ethynylestradiol (EE2), estrone (E1), beta-estradiol (E2), and estriol (E3) have been determined, from tests carried out in the pH r...

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