The reagent (S)-5-methoxy-2-[[(4-methoxy-3, 5-dimethyl-2-pyridinyle-methyle] sulfinyle]-1H-benzimidazole gives greenish yellow coloration with V (V) as well as Co (II) in basic medium. This observation is used for the simultaneous determination of both the metal ions using Zero and second order derivative spectrophotometry. Optimum conditions were established for this determination. Job’s and m...

The degradation behavior of cefixime trihydrate was investigated under different stress conditions of acidic hydrolysis, alkaline hydrolysis and oxidation using spectrophotometry. Stability indicating spectrophotometric methods were developed that could separate the drug from its degradation products formed under these stress conditions. The UV spectral characteristics of the drug and degraded ...

The simultaneous determination of albendazole (ABZ) and praziquantel (PZQ) was performed by different mathematical approaches: second derivative spectrophotometry (SDS), classical least squares, regression of partial least squares and principal components regression based on spectral data of drugs dissolved in methanol-hydrochloric acid solution. The detection limits for multivariate calibratio...

The H-point standard addition method (HPSAM) was applied to the simultaneous determination of Bi(III) and Sb(III). This method is based on the difference in the absorbance of complexes of Bi(III) and Sb(III) with iodide in acidic media in different wavelength pairs. The results showed that Bi(III) and Sb(III) can be determined simultaneously with concentration ratios of 15:1 to 1:20. First-deri...

Buprenorphine is a partial mu agonist and kappa antagonist which is used for the treatment of pain and opioid addiction. A mixture of buprenorphine hydrochloride and naloxone hydrochloride has been approved for the treatment of opioid dependence.In this study a third order derivative spectrophotometric method based on zero-crossing technique has been used for the simultaneous determination of b...

Haloperidol (i.e. HPD) and hydroxyzine (i.e. HXY), two effective and important tranquilizers with low redox activity, were found to generate an irreversible anodic peak at about +0.86 V (vs. SCE) or two anodic peaks at about +0.83 and +0.91 V in 0.05 M NaH₂PO₄-Na₂HPO₄ (pH=7.0) buffer solution with a multi-walled carbon nanotubes-modified glassy carbon electrode (i.e. MWNTs/GC), respectively. Th...