Methods Between 2004 and 2009 the basic genetic screen encompassed FMF gene MEFV exons 2 and 10; TRAPS gene TNFRSF1A exons 2-6; MKD gene MVK exons 9 and 11 and CAPS gene NLRP3/CIAS1 exon 3. When deemed appropriate, these tests were extended to additional exons on a case by case basis. From 2010 additional genes were added to our repertoire: NOD2 (exons 2 and 4) associated with Crohn’s Disease a...

The amphipod Parhyale hawaiensis is a small crustacean found in intertidal marine habitats worldwide. Over the past decade, Parhyale has emerged as a promising model organism for laboratory studies of development, providing a useful outgroup comparison to the well studied arthropod model organism Drosophila melanogaster. In contrast to the syncytial cleavages of Drosophila, the early cleavages ...

PURPOSE Although replacement of the ureter with a bowel segment is indicated for large ureteral defects, it is still a challenging technique for urologists. We present our experience and outcome of ureteral reconstruction using bowel segments. MATERIALS AND METHODS Ureteral reconstruction with bowel segments was performed in eight patients in our institute between 1969 and 2009. We investigat...

The development of a series of sin~le-stage, oilfree screw air compressors with a compression ratio of 8, previously obtainable only with two-sta~e compressors, is described. A new rotor profile, which reduces leakage loss to achieve higher efficiency, and desig-ned for ease of manufacture, is detailed. Additionally, a new desig-n method for the clearance between rotors, to compensate for rotor...

Here, we report draft genome sequences of 26 isolates of Salmonella enterica subsp. enterica, representing eight serotypes, which were isolated from cows in a Pennsylvania dairy herd, the farm on which they were reared, and the associated off-site heifer-raising facility over an 8-year sampling period.

Legs are the most important elements for accomplishing human physical work including transportation or displacement. The article presents a mechanical reproduction of the human walking apparatus. Using design rules, a final mechanism configuration is achieved such that the crank is a binary link connected to a binary ground link. The resulting linkage is a single degree-of-freedom (DOF) eight-b...

The objective of this study was to replicate the association between atypical handedness and psychosis-proneness in a representative sample of adolescents from the general population. It expands previous studies by (1) analyzing a variety of atypical handedness indexes (left, mixed, ambiguous, and inconsistent), (2) measuring comprehensively the multidimensionality of psychosis-proneness, and (...

A randomised double-blind placebo-controlled trial of intravenous methylprednisolone versus oral methylprednisolone at equivalent high dose was carried out on 35 patients with an acute relapse of multiple sclerosis (MS). After baseline evaluation each was randomly allocated to oral treatment and intravenous placebo or intravenous treatment and oral placebo, receiving 500 mg of methylprednisolon...

We give twenty eight diverse proofs of the fundamental Euler sum identity ζ(2, 1) = ζ(3) = 8 ζ(2, 1). We also discuss various generalizations for multiple harmonic (Euler) sums and some of their many connections, thereby illustrating the wide variety of techniques fruitfully used to study such sums and the attraction of their study.