This work reports the development of a simple and rapid electrochemical immunosensor for determination breast cancer biomarker Cancer Antigen 15–3 (CA 15–3). Disposable cost-effective chips, consisting gold screen-printed electrodes (AuSPEs), were used to develop portable devices monitoring in point-of-care (PoC), under clinical context. The biosensor preparation consisted two steps. First, sel...

Urea is an added value chemical with wide applications in the industry and agriculture. The release of urea waste to environment affects ecosystem health despite its low toxicity. Online monitoring for industrial environmental unaddressed challenge. Electroanalytical techniques can be a smart integrated solution online if sensors overcome major barrier associated long-term stability. Mixed meta...

Exosomes are both active in mediating intracellular communication and potentially present a potent cargo of disease biomarkers to an assay. The robust evaluation of exosomal markers could lead to a paradigm shift in clinical analysis and associated care. To date, much of this has been hindered by issues of sample preparation and assay signal-to-noise. We introduce here the use of ultrasensitive...

Recent work on the preparation of highly organized macroporous electrodes and nanoporous ultramicroelectrodes has been combined and extended to elaborate macroporous ultramicroelectrodes (UMEs) by template synthesis using colloidal crystals and following two different and complementary methods. On the one hand, arched porous UMEs were prepared, and on the other hand, cylindrical porous UMEs wer...

This work describes the adaptive use of conventional stainless steel pins-used in unmodified form or coated with carbon paste-as working, counter, and quasi-reference electrodes in electrochemical devices fabricated using cotton thread or embossed omniphobic R(F) paper to contain the electrolyte and sample. For some applications, these pin electrodes may be easier to modify and use than printed...

Abstract Electroanalytical and optical techniques are widely used in the development of nanomaterials-based sensor platforms. These have a quick response, high sensitivity, selectivity. nanomaterial-based sensors must be able to detect biomarkers, pathogens, toxins, pharmaceuticals biological matrices associated with cardiovascular disease, cancer, neurodegenerative diseases. Considering these ...

The present review article presents and discusses automated sequential injection (SI) based methods for the determination of pharmaceutically and biologically important thiols, namely cysteine, N-acetylcysteine, penicillamine, glutathione and captopril. The review intends to cover a range of ten years of published research on this topic (2000 – 2009). The methods are classified according to the...