A new analytical method had been developed to enable high-spatial-resolution (U–Th)/He dating of accessory minerals. It involves the use of a focused ArF excimer to ablate pits in a polished grain surface, with the evolved gases spiked for isotope-dilution measurement of radiogenic He. These data are converted to concentrations by precise measurement of each pit using an optical interferometric...

The Sungun porphyry copper deposit that intruded Eocene volcano sedimentary and Cretaceous carbonate rocks hosted by a diorite/granodioritic to quartzmonzonitic stock. Copper mineralization is essentially associated more with potassic and less phyllic alteration. Therefore separating these two kinds of alteration is so important. In this paper, by applying the discriminant, it was attempt to se...

The crystal structure of the complex pi-AlFeMgSi phase, which was previously thought to have the composition Al(8)FeMg(3)Si(6), has been investigated. Microprobe analysis revealed that the phase has a different composition, Al(9)FeMg(3)Si(5). The space group was determined and confirmed to be P62m with the use of parallel-beam electron diffraction (SAD) and convergent-beam electron diffraction ...

We are thankful for the comments on ‘Sodium glucose co-transporter (SGLT2) inhibitor: Patient safety and clinical importance’, and we appreciate the concern raised for its risk of euglycemic diabetic ketoacidosis (DKA). During clinical development programs for a new drug approval, it is not uncommon that some unexpected safety issues may go unobserved. Interestingly, the incidence of ketoacidos...

We present high-precision measurements of pure element stable isotope pairs that demonstrate mass has no influence on the backscattering of electrons at typical electron microprobe energies. The traditional prediction of average backscatter intensities in compounds was pragmatically based on elemental mass fractions. Our isotopic measurements establish that this approximation has no physical ba...

We demonstrate an optical technique, called laser-gain scanning microscopy (LGSM), to map dopant concentration profiles in engineered laser gain-media. The performance and application range of this technique are exampled on a Nd(3+) concentration profile embedded in a YAG transparent ceramic sample. Concentration profiles measured by both LGSM and SIMS techniques are compared and agree to withi...

Empagliflozin has been shown to improve glycaemic control and reduce CV mortality along with salutary effects on renal outcomes as compared to placebo in a recently conducted EMPA-REG OUTCOME trial in a large number of patients.[1,2] In this study, more than 7000 patients were randomly assigned to receive empagliflozin in the dose of 10 mg or 25 mg or placebo once daily. Patients were followed ...

Sixth millennium BC Dalma ceramics from the northwestern and central Zagros have previously been described as beingimpossible to distinguish using decorative style analysis in spite of the great distance between the two regions. In thisstudy, petrographic (thin section) analysis and a small-scale electron microprobe project was carried out on the ceramicsof the two regions, as well as a small s...