In order to understand the mechanisms involved in the extraction processes developed to separate minor actinides, the “ligand/metallic cation” complexes formed in the organic phases are characterized by electrospray ionization-mass-spectrometry (ESI-MS). This paper deals with the application of the ESI-MS technique to analyze americium complexes in organic solutions. Two extractant systems are ...

Two new phenyl glycosides, mangliesides A and B (1, 2), a new ionol glycoside, manglieside C (3), two new lignan glycosides, mangliesides D and E (4, 5), were isolated from the leaves of Manglietia phuthoensis, along with two known lignans, 3-methoxymagnolol (6) and obovatol (7). Their structures were established by means of 1D and 2D NMR, electrospray ionization (ESI)-MS and HR-ESI-MS experime...

This short review presents new insights on the mechanism and online monitoring using electrospray ionization tandem mass spectrometry (ESI-MS/MS) of Morita-Baylis-Hillman (MBH) reactions. MBH reactions are versatile carbon-carbon organocatalyzed bond forming reactions, making them environmentally friendly due to general organocatalysts employed. The organocatalyst behavior, which controls the t...

Bioaffinity mass spectrometry screening is a novel approach using non-denaturing electrospray ionization (ESI) mass spectrometry (MS) in identifying drug leads. This screening technique can detect and preserve noncovalent protein-active drug ligand complexes under different physiological conditions. Although there are many successful screening campaigns employing this technique, the big challen...

Electrospray ionization mass spectrometry (ESI-MS) has become one of the most popular and powerful technologies to identify and quantify individual lipid species in lipidomics. Meanwhile, quantitative analysis of lipid species by ESI-MS has also become a major obstacle to meet the challenges of lipidomics. Herein, we discuss the principles, advantages, and possible limitations of different mass...

We demonstrate a two-dimensional (2D) separation microchip allowing capillary isoelectric focusing-capillary zone electrophoresis (cIEF-CZE) to be coupled to electrospray ionization mass spectrometry (ESI/MS). In the first dimension, separation is according to pI values (cIEF), while CZE occurs in the second dimension during mobilization towards the monolithically integrated ESI emitter. The se...

An improved analytical method was developed for identifying sulfide compounds from aromatic fractions in Lungu atmospheric residue (LGAR). Sulfides aromatics were selectively oxidized into sulfoxides using tetrabutyl ammonium periodate (TBAP) and identified by positive-ion Electrospray Ionization Source (ESI) Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). Results showe...

A simple and rapid method involving high-performance liquid chromatographic separation, followed by photodiode array (PDA) and electrospray ionization-mass spectrometric (ESI-MS) detection of aromatic sulfonates in waste-water effluents of industrial units producing optical whitening agents, has been developed. The separation was achieved on a reversed-phase Hypersil C18 column using gradient e...

A method for increasing the productivity of ESI LC-MS/MS (electrospray ionization-liquid chromatography-tandem mass spectrometry) was proposed and applied. After IF (isoelectric focusing) of the sample using IPG (immobilized pH gradient) strip, the strip was cut to sections, and every section was treated according to trypsinolysis protocol for MS/MS analysis. The peptides produced were further ...

Intact, nonvolatile, biological macromolecules can be transferred directly from the solid state into the gas phase, in ambient air, for subsequent mass spectral analysis using non-resonant femtosecond (fs) laser desorption combined with electrospray ionization (ESI). Mass spectral measurements for neat samples, including a dipeptide, protoporphyrin IX and vitamin B12 adsorbed on a glass insulat...