The activity of the exogenous, full-length insulin-like growth factor-2 (IGF-2) P3 promoter is significantly up-regulated during the logarithmic growth phase but rapidly declines in confluent CaCo2 cells undergoing differentiation. Nuclear run-on assays confirmed cell density-dependent regulation of endogenous P3 promoter. To identify regulatory elements in the P3 promoter that may be required ...

Protooncogene fos is rapidly and transiently induced by nerve growth factor (NGF) in rat pheochromocytoma PC12 cells. Two adjacent promoter elements have been identified to mediate the NGF response. One element colocalizes with the serum response element (SRE) centered at position -308, previously shown to confer inducibility by serum, phorbol 12-myristate 13-acetate, and epidermal growth facto...

Thermogenesis against cold exposure in mammals occurs in brown adipose tissue (BAT) through mitochondrial uncoupling protein (UCP1). Expression of the Ucp1 gene is unique in brown adipocytes and is regulated tightly. The 5'-flanking region of the mouse Ucp1 gene contains cis-acting elements including PPRE, TRE, and four half-site cAMP-responsive elements (CRE) with BAT-specific enhancer element...

This report considers the feasibility of using computer models for developing expedient soil stabilization technique.". Of major Importance is the Increase in soil strength necessary to provide specified degrees of vehicle mobility and dust or erosion control. The merits of pursuing this task at the molecular level are considered and it is decided that application of electro-chemical theory is ...

Ion mobility spectrometers (IMS) are versatile gas analyzers. Due to their small size and robustness, combined with a very high sensitivity, they are often used in gas sensing applications such as environmental monitoring. In order to improve the selectivity, they are typically combined with a mass spectrometer (MS). Since IMS works at atmospheric pressure, and MS works at vacuum, a special int...

The mobility of entrepreneurs, which is an integral part of human life, can occur in all aspects of occupation and location. Finding out the general trends of mobility in entrepreneurship can be used in the effective motivational activities. As Sylhet is a remittance and raw materials rich but industrially backward area, the mobility of entrepreneurship in both aspects in this area is to be ana...

the phenomenological model of khossravi and connors (1992) has been adopted to calculate the electrophoretic mobility of drugs at different concentrations of solvents in a binary mixture. the accuracy and predictability of the model have been evaluated employing 14 experimental data sets by using average percentage mean deviation (apmd). the obtained apmd for correlative and predictive studies ...

A current controlled bistable switching element using a CW Gunn diode is reported. With modest circuits switching rates of the order of 10 MHz have been obtained. Switching is initiated by current pulses of short duration (5 10 ns). Rise times of the order of several nanoseconds could be obtained. The apparent mechanism which allows the bistable operation of the Gunn diode is the reduction in t...

Center-point model of deformable surface for segmentation of 3D images is presented. Mobility of each node, element composing the surface, is constrained in the model to one direction. Also an original formula for image influence computation is proposed. The model aims at algorithm simplification and reduction of computational time needed for segmentation of 3D imaging data acquired from magnet...

In this paper we show guidelines for performance testing through BRAIN Candidate Mobility Management Protocol (BCMP). At first, we investigate the main issues of our tests, then we describe briefly the applied TTCN-3 based distributed parallel test environment. We present the structure of the network to be tested and the Mobile Node Emulator, the main functional element of the performance test....