نتایج جستجو برای: embryo abnormalities

تعداد نتایج: 167924  

Journal: :Human reproduction update 2011
Jannie van Echten-Arends Sebastiaan Mastenbroek Birgit Sikkema-Raddatz Johanna C Korevaar Maas Jan Heineman Fulco van der Veen Sjoerd Repping

BACKGROUND Although chromosomal mosaicism in human preimplantation embryos has been described for almost two decades, its exact prevalence is still unknown. The prevalence of mosaicism is important in the context of preimplantation genetic screening in which the chromosomal status of an embryo is determined by the analysis of a single cell from that embryo. METHODS Here we report a systematic...

Journal: :the archives of bone and joint surgery 0
edward k. rodriguez orthopedic trauma beth israel deaconess medical center, harvard medical school, boston, usa jeeva munasinghe national institute of neurological disorders and stroke, national institutes of health, bethesda, usa

background: in this feasibility study, a mechanically loaded in-vitro tissue culture model of joint morphogenesis using the isolated lower extremity of the 8 day old chick embryo was developed to assess the effects of mechanical loading on joint morphogenesis. methods: the developed in-vitro system allows controlled flexion and extension of the chick embryonic knee with a range of motion of 20 ...

Journal: :Human molecular genetics 2015
Eric de Waal Lisa A Vrooman Erin Fischer Teri Ord Monica A Mainigi Christos Coutifaris Richard M Schultz Marisa S Bartolomei

Assisted reproductive technologies (ART) are associated with several complications including low birth weight, abnormal placentation and increased risk for rare imprinting disorders. Indeed, experimental studies demonstrate ART procedures independent of existing infertility induce epigenetic perturbations in the embryo and extraembryonic tissues. To test the hypothesis that these epigenetic per...

2006
M A Potter

Advice is provided on five questions that were addressed by subjecting emu eggs, as a model for kiwi eggs, to transport-induced jarring during three stages of embryo development. The jarring associated with two kiwi egg recovery operations was also measured. Jarring during transportation had no demonstrable effect on embryo development, the need for hatching assistance, or the incidence of embr...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2017
Jiawei Xu Zhen Zhang Wenbin Niu Qingling Yang Guidong Yao Senlin Shi Haixia Jin Wenyan Song Lei Chen Xiangyang Zhang Yihong Guo Yingchun Su Linli Hu Jun Zhai Yile Zhang Fangli Dong Yumei Gao Wenhui Li Shiping Bo Mintao Hu Jun Ren Lei Huang Sijia Lu X Sunney Xie Yingpu Sun

Reciprocal translocations (RecT) and Robertsonian translocations (RobT) are among the most common chromosomal abnormalities that cause infertility and birth defects. Preimplantation genetic testing for aneuploidy using comprehensive chromosome screening for in vitro fertilization enables embryo selection with balanced chromosomal ploidy; however, it is normally unable to determine whether an em...

Journal: :Human reproduction 1999
S Munné C Magli J Cohen P Morton S Sadowy L Gianaroli M Tucker C Márquez D Sable A P Ferraretti J B Massey R Scott

usromosomal abnormalities are responsible for a great deal of embryo wastage, which is reflected, at least partially, in decreased implantation and increased miscarriage in older women. To address this problem the transfer of only chromosomally normal embryos previously selected by preimplantation genetic diagnosis (PGD) has been proposed. We designed a multi-centre in-vitro fertilization (IVF)...

Journal: :Developmental dynamics : an official publication of the American Association of Anatomists 1998
I Leconte J C Fox H S Baldwin C A Buck J L Swain

Fibroblast growth factors (FGFs) are expressed in the developing embryo and are postulated to regulate embryonic and vascular growth. The goal of this study was to elucidate the role of basic fibroblast growth factor (FGF-2) in early murine embryonic cardiovascular development in the mouse embryo. Gestation day 7.5 embryos were harvested and placed in culture, and 12 hr later replication-defect...

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