Introduction: Accuracy of SNP-based whole-genome phylogeny reconstruction relies heavily on quality of sequence alignment which is particularly hindered by poorly assembled genomes. Alignment-free methods might provide additional insights. Here, we constructed a wholegenome phylogeny of 9 outbreak isolates against existing E. coli genomes using the alignment-free feature frequency profile (FFP)...

The defects of the alveolar ridge can result from various causes, most common being the collapse of alveolar bone during extraction. Localized defects of alveolar crest impair prosthetic rehabilitation due to poor emergence profile of function. Several alternatives have been proposed to restore the damaged ridge by hard and soft tissue augmentation. Various soft tissue ridge augmentation techni...

We study BAL variations of SDSS J141955.28+522741.4 utilizing 32 epochs of spectroscopic observations from SDSS. We identify three individual BAL troughs for C iv and one BAL trough for Si iv. The deepest C iv BAL trough shows significant EW variations in timescales of a few 10 h. The fast component of the deepest C iv BAL presents disappearance and re-emergence preserving its initial velocity ...

We use a lattice Boltzmann algorithm for liquid-gas coexistence to investigate the steady-state interface profile of a droplet held between two shearing walls. The algorithm solves the hydrodynamic equations of motion for the system. Partial wetting at the walls is implemented to agree with Cahn theory. This allows us to investigate the processes which lead to the motion of the three-phase cont...

We propose a new model of cluster growth according to which the probability that a new unit is placed in a point at a distance r from the city center is a Gaussian with mean equal to the cluster radius and variance proportional to the mean, modulated by the local density ρ(r). The model is analytically solvable in d = 2 dimensions, where the density profile varies as a complementary error funct...

Population aging is leading to the emergence in recent years of a new “clinical phenotype” characterized by the summation of several diseases (polypathologies) [1] with the subsequent accumulation of therapies (polypharmacy) [2] often on the advices received from different specialists and, every now and then, with a lack of harmonization or continuity [2-4]. Among the drugs most frequently pres...

The emergence of multidrug-resistant Enterobacteriaceae strains producing carbapenemases, such as NDM-1, has become a major public health issue due to a high dissemination capacity and limited treatment options. Here we describe the draft genome of three NDM-1-producing isolates: Providencia rettgeri (CCBH11880), Enterobacter hormaechei subsp. oharae (CCBH10892) and Klebsiella pneumoniae (CCBH1...

With conventional fixed dental prostheses, the interim restoration is a valuable diagnostic tool in the evaluation of esthetics and function. To achieve predictable definitive esthetic results, information about the subgingival and the supragingival contour of a properly designed restoration should be communicated to the dental laboratory technician. The technique described enables the accurate...

The emergence of investor-owned firms as major actors in U.S. health care financing and delivery has led to calls for federal and state intervention to protect nonprofits and to stem the for-profit sector's growth. High-profile scandals involving some of these firms have lent urgency to such proposals. This paper considers the case for government intervention to protect the nonprofit health sec...

Stress fibers are contractile actomyosin bundles commonly observed in the cytoskeleton of metazoan cells. The spatial profile of the polarity of actin filaments inside contractile actomyosin bundles is either monotonic (graded) or periodic (alternating). In the framework of linear irreversible thermodynamics, we write the constitutive equations for a polar, active, elastic one-dimensional mediu...