skeletal involvement is the second most common site of metastases after lymph nodal metastases in patients with prostate cancer. the skeletal metastases from prostate cancer are osteoblastic in nature and show increased tracer avidity on the bone scan. focal tracer avid lesion in skeleton especially in skull requires the careful examination by further investigation. the patients with skull meta...

Introduction: In Single Photon Emission Computed Tomography (SPECT), the projection data used for image reconstruction are distorted by several factors, including attenuation and scattering of gamma rays, collimator structure, data acquisition method, organ motion, and washout of radiopharmaceuticals. All these make reconstruction of a quantitative SPECT image very difficult. Simulation of a SP...

Gliomas account for almost 80% of primary malignant brain tumors in adults. Magnetic Resonance imaging (MRI) is still the gold standard for diagnosis of brain tumors and brain 99mTc-tetrofosmin Single Photon Emission Computed Tomography (99mTc-tetrofosmin-SPECT) has been established as a useful tool for their evaluation. Fluorine-18–2-fluoro-2-deoxy-d-glucose positron emi...

The single-vibronic-level (SVL) emission spectra of HAsO and DAsO have been simulated by electronic structure/Franck-Condon factor calculations to confirm the spectral molecular carrier and to investigate the electronic states involved. Various multi-reference (MR) methods, namely, NEVPT2 (n-electron valence state second order perturbation theory), RSPT2-F12 (explicitly correlated Rayleigh-Schr...

Introduction: To investigate the effects of breathing cycle and tree diaphragm motions on prostate cancer tumors standard uptake value (SUV) during positron emission tomography (PET) and to correct it. Materials and methods: Respiratory motion traces were simulated on the common patient breathing cycle and tree diaphragm motio...

The Geant4 Application for Emission Tomography (GATE) is an advanced open-source software dedicated to Monte-Carlo (MC) simulations in medical imaging involving photon transportation (Positron emission tomography, single photon emission computed tomography, computed tomography) and in particle therapy. In this work, we extend the GATE to support simulations of optical imaging, such as biolumine...

Combined positron-emission tomography–computed tomography is becoming a widely used imaging technique in nuclear medicine and nuclear radiology. Its unique dual functional-anatomical imaging capacity is highly complementary to conventional imaging, and it has become an integral part of the multidisciplinary clinical management of cancer in Hong Kong. The clinical value, efficacy, limitations, a...

Imaging of the lungs in patients with asthma has evolved dramatically over the last decade with sophisticated techniques, such as computed tomography, magnetic resonance imaging, positron emission tomography, and single photon emission computed tomography. New insights into current and future modalities for imaging in asthmatic patients and their application are discussed to potentially shed a ...

This image based series comprises of a quiz pertaining to the identification of salient anatomical structures expected to be seen at a given level on the computed tomography (CT) followed by examples of multiple representative pathologies that can be seen at the same level in a routine clinical setting. It is expected that this will improve confidence of nuclear physicians in interpretation of ...