نتایج جستجو برای: emulsion vaccine

تعداد نتایج: 120149  

2015
W. P. Zhou H. Y. Hua P. C. Sun Y. X. Zhao

The purpose of the present study was to develop the Solutol HS15-based doxorubicin submicron emulsion with good stability and overcoming multi-drug resistance. In this study, we prepared doxorubicin submicron emulsion, and examined the stability after autoclaving, the in vitro cytotoxic activity, the intracellular accumulation and apoptpsis of doxorubicin submicron emulsion in MCF-7/ADR cells. ...

A. Mohammadi, H. Tavakkoli K. Asasi,

The objective of this study was to compare the effect of two conventional H9N2 avian influenza (AI) vaccines on replication and shedding of the H9N2 AI virus in broiler chickens. These inactivated oil emulsion vaccines contain either a UAE or an Iranian H9N2 AI isolate. One hundred and fifty one-day-old commercial broiler chickens were randomly divided into six groups. The birds, except for the...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2011
Anja Seubert Samuele Calabro Laura Santini Barbara Galli Alessia Genovese Sara Valentini Susanna Aprea Annalisa Colaprico Ugo D'Oro Marzia M Giuliani Michele Pallaoro Mariagrazia Pizza Derek T O'Hagan Andreas Wack Rino Rappuoli Ennio De Gregorio

Oil-in-water emulsions have been successfully used to increase the efficacy, immunogenicity, and cross-protection of human vaccines; however, their mechanism of action is still largely unknown. Nlrp3 inflammasome has been previously associated to the activity of alum, another adjuvant broadly used in human vaccines, and MyD88 adaptor protein is required for the adjuvanticity of most Toll-like r...

Journal: :Revue scientifique et technique 1991
H B Huang

Viral haemorrhagic disease (VHD) of rabbits is an acute entity with high mortality which affects adult rabbits. Several vaccines have been developed in China and extensive use of these vaccines in the field has controlled the spread of the disease. Formalin inactivated tissue vaccine induces solid immunity on the third to fourth day post vaccination and immunity lasts for at least six months. T...

Journal: :Clinical and vaccine immunology : CVI 2016
Susan L Baldwin Valerie A Reese Po-Wei D Huang Elyse A Beebe Brendan K Podell Steven G Reed Rhea N Coler

Mycobacterium tuberculosis HN878 represents a virulent clinical strain from the W-Beijing family, which has been tested in small animal models in order to study its virulence and its induction of host immune responses following infection. This isolate causes death and extensive lung pathology in infected C57BL/6 mice, whereas lab-adapted strains, such as M. tuberculosis H37Rv, do not. The use o...

Journal: :Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2010
Sivagurunathan Moni Sivakumar Natarajapillai Sukumaran Loganathan Nirmala Rathinavel Swarnalakshmi Botta Anilbabu Lakshmanan Siva Jayaraman Anbu Thukani Sathanantham Shanmugarajan Velayudam Ravichandran

BACKGROUND/PURPOSE The purpose of this research was to develop an alternative adjuvant for hepatitis B vaccine (HBsAg) that elicits a long-lasting immune response after a single administration. In this study, the suitability of Poly (D, L)-lactide-co-glycolic acid (PLGA), Poly lactic acid (PLA) and Chitosan polymers as adjuvants for HBsAg were investigated. METHODS We used solvent evaporation...

Journal: :Langmuir : the ACS journal of surfaces and colloids 2015
Kazuki Akamatsu Shosuke Kanasugi Shin-ichi Nakao David A Weitz

In this study, a membrane-integrated glass capillary device for preparing small-sized water-in-oil-in-water (W/O/W) emulsion droplets is demonstrated. The concept of integrating microfluidics to prepare precise structure-controlled double emulsion droplets with the membrane emulsification technique provides a simple method for preparing small-sized and structure-controlled double emulsion dropl...

Journal: :international journal of bio-inorganic hybrid nanomaterials 0

the purpose of this study was to produce oil in water nano-emulsion by ultrasonication, and investigate the influence of inulin and β-cyclodextrin on the prosperities of nano-emulsion and morphology of spray dried microcapsules. the results showed that emulsion droplet size in samples containing β-cyclodextrin (8.28±0.11 nm) was less than inulin samples (97.12±4.2 nm). considering sem photos, β...

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