A patient with Shy-Drager syndrome who presented with severe angina pectoris is described. Special investigations of his autonomic nervous system showed sympathetic and parasympathetic dysfunction with supersensitive end-organ response. Sympathetic dysfunction manifested as labile hypertension, severe postural hypotension, and inadequate heart rate response to atropine and the Valsalva manoeuvr...

The anginal threshold was determined by atrial pacing in 23 patients with coronary artery disease. Twelve of the 23 subjects also performed supine exercise at progressive workloads until the onset of angina. Atrial pacing produced a fall in left ventricular stroke work index and left ventricular end-diastolic pressure (LVEDP); cardiac output increased, and, with the onset of angina, left ventri...

absractthis study investigated a 63-day boy with end stage renal disease and abdominalcysts. the antenatal sonography detected anhydraminos, posterior urethral valve,and cystic dysplastic kidneys. voiding cystourethrogram revealed two obstructivegiant diverticula which at first looked like enlarged renal pelvis. the patient had persistenturinary tract infection and perforation of diverticula. t...

Changes in left ventricular size may be of importance in the development of angina and in its amelioration by glyceryl trinitrate, but left ventricular dimensions have not been measured during exercise in the upright position, the circumstance in which angina most often occurs. To assess changes in left ventricular end-systolic and end-diastolic dimensions, echocardiograms were obtained from 5 ...

OBJECTIVES This study evaluates the feasibility and safety of a catheter-based laser system for percutaneous myocardial revascularization and analyses the first clinical acute and long-term results in patients with end-stage coronary artery disease (CAD) and severe angina pectoris. BACKGROUND In patients with CAD and intractable angina who are not candidates for either coronary artery bypass ...

The hemodynamic responses of nine patients with severe coronary artery disease were studied during the precipitation of angina by both supine exercise and increasing rates of atrial pacing. Tension-time index and the first derivative of left ventricular pressure pulse (LV dp/dt) at the onset of angina were significantly higher (P < 0.01) in each patient when angina was induced by exercise than ...

BACKGROUND 'Typical' angina is often used to describe symptoms common among men, while 'atypical' angina is used to describe symptoms common among women, despite a higher prevalence of angina among women. This discrepancy is a source of controversy in cardiac care among women. OBJECTIVES To redefine angina by (1) qualitatively comparing angina symptoms and experiences in women and men and (2)...

The anginal threshold was determined by atrial pacing in 23 patients with coronary artery disease. Twelve of the 23 subjects also performed supine exercise at progressive workloads until the onset of angina. Atrial pacing produced a fall in left ventricular stroke work index and left ventricular end-diastolic pressure (LVEDP); cardiac output increased, and, with the onset of angina, left ventri...

BACKGROUND Unfractionated heparin has been used extensively for the treatment of unstable angina/non-Q wave myocardial infarction but it has several disadvantages. Low-molecular weight heparins are now recommended although they are 3-5 times costlier than unfractionated heparin since they are convinient to administer and do not require activated thromboplastin time monitoring. Whereas enoxapari...

RATIONALE The effect of stem/progenitor cells on myocardial perfusion and clinical outcomes in patients with refractory angina remains unclear because studies published to date have been small phase I-II trials. OBJECTIVE We performed a meta-analysis of randomized controlled trials to evaluate the effect of cell-based therapy in patients with refractory angina who were ineligible for coronary...