Enzymes are becoming increasingly important tools for synthesizing and modifying fine and bulk chemicals. The availability of biocatalysts which fulfil the requirements of industrial processes is often limited. Recruiting suited enzymes from natural (e.g. metagenomes) and artificial (e.g. directed evolution) biodiversity is based on screening libraries of microbial clones expressing enzyme vari...

Mass spectrometry based technologies are promising as generalizable high-throughput assays for enzymatic activity. In one such technology, a specialized enzyme substrate probe is presented to a biological mixture potentially exhibiting enzymatic activity, followed by an in situ enrichment step using fluorous interactions and nanostructure-initiator mass spectrometry. This technology, known as N...

in recent years, work for the information profession has become characterized by fast-paced change and new skills requirements. this transformation has been brought about by the constant emergence of relevant new technologies. in this paper, ict skills for professionals in developing countries are examined and nigeria research project is mentioned as an example. one of the important implication...

Despite the growing impact of enzyme catalysis in industrial chemistry, full potential this technology is yet to be unlocked. Accessing new chemistries and expanding scope existing reactions necessary order make biocatalysis a pivotal manufacturing chemicals across whole spectrum. This review highlights how biocatalytic toolbox for synthetic chemistry has recently been expanded by extending ind...

Directed evolution has become an important enabling technology for the development of new enzymes in the chemical and pharmaceutical industries. Some of the most interesting substrates for these enzymes, such as polymers, have poor solubility or form highly viscous solutions and are therefore refractory to traditional high-throughput screens used in directed evolution. We combined digital imagi...

Conducting polymers have emerged as potential candidates for biosensors. Due to their straightforward preparation methods, unique properties, and stability in air, conducting polymers have been applied to energy storage, electrochemical devices, memory devices, biosensors, and electro catalysts. Many research studies have been conducted on the use of conjugated polymers in the construction of c...

UNLABELLED Deacetylcephalosporin C synthase (DACS), a 2-oxoglutarate-dependent oxygenase synthesized by Streptomyces clavuligerus, transforms an inert methyl group of deacetoxycephalosporin C (DAOC) into an active hydroxyl group of deacetylcephalosporin C (DAC) during the biosynthesis of cephalosporin. It is a step which is chemically difficult to accomplish, but its development by use of an en...

Biotechnological and industrial processes involve applications of various microorganisms enzymes, laccase, as a multifunctional enzyme, is admired for its role in degrading variety substances. Laccase copper-containing oxidase enzyme that usually found insects, plants, including fungi archaea. Several phenolic substrates are oxidized by laccases, which results crosslinking. Various research wor...

Enzyme-Photo-coupled Catalytic System (EPCS) integrates the light absorption capacity of photocatalysts and high activity/specificity enzymes, which is becoming an emerging technology platform to mimic natural photosynthesis for harnessing solar energy generate valuable products, including bulk chemicals, chemicals pharmaceutical chemicals. Cofactors NAD(P)+/NAD(P)H, as “energy currency”, are i...

The abundant biomass polysaccharides in nature can be degraded into oligo-oligosaccharides or monosaccharides. These sugars with small molecule used to produce ethanol, pharmaceutical products and other chemical materials. structure of plant is very complex, its degradation involves the synergistic catalysis various glycoside hydrolases, such as xylanase, glucanase, cellulose. Compared a single...