epidermal growth factor

نتایج جستجو برای: epidermal growth factor

تعداد نتایج: 1474872 فیلتر نتایج به سال:

Epidermal growth factor receptor and KRAS mutations in Brazilian lung cancer patients

2012

Carlos E. Bacchi Heloísa Ciol Eduardo M. Queiroga Lucimara C. Benine Luciana H. Silva Elida B. Ojopi

OBJECTIVE Epidermal growth factor receptor is involved in the pathogenesis of non-small cell lung cancer and has recently emerged as an important target for molecular therapeutics. The KRAS oncogene also plays an important role in the development of lung cancer. The aim of this study was to evaluate the frequency of epidermal growth factor receptor and KRAS mutations in a population of Brazilia...

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Human epidermal growth factor receptor 2-positive metastatic breast cancer with novel epidermal growth factor receptor -ZNF880 fusion and epidermal growth factor receptor E114K mutations effectively treated with pyrotinib

Journal: :Medicine 2020

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Differential activity of 2-methylene-19-nor vitamin D analogs on growth factor gene expression in rhino mouse skin and comparison to all-trans retinoic acid

2017

Jamie M Ahrens James D Jones Nirca J Nieves Ann M Mitzey Hector F DeLuca Margaret Clagett-Dame

While all 2-methylene-19-nor analogs of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3) tested produce an increase in epidermal thickness in the rhino mouse, only a subset reduce utricle size (comedolysis). All-trans retinoic acid (atRA) also causes epidermal thickening and a reduction in utricle size in the rhino mouse. We now report that 2-methylene-19-nor-(20S)-1α-hydroxybishomopregnacalciferol (2M...

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