Erythema nodosum leprosum is defined by the appearance of tender skin nodules, which can be accompanied by fever, joint pain, neuritis, edema, malaise and/or lymphadenopathy. The authors describe the case of a 19-year-old Angolan black woman, resident in Portugal for the last 10 years, diagnosed with Hansen's disease at the age of 12, irregular with follow-up and non-compliant with treatment. S...

OBJECTIVE Interleukin (IL)-22 has been reported to be involved in the development of autoimmune diseases. This study aimed to analyze the expression and potential role of IL-22 in the pathogenesis of Behcet's disease (BD). METHODS The levels of IL-22 in patient sera or supernatants of cultured peripheral blood mononuclear cells (PBMCs) and CD4(+)T cells were detected by enzyme-linked immunoso...

T case was notable because the initial presentation of Crohn’s disease consisted only of extraintestinal manifestations. This is uncommon, and the vast majority of children will present with the typical combination of abdominal pain, diarrhea and weight loss with or without extraintestinal manifestations (Box 1). Extraintestinal manifestations occur in about 25%–35% of cases of inflammatory bow...

INTRODUCTION There has been an increasing number of tuberculosis cases worldwide, but tuberculosis of the breast remains rare. In rare cases this is seen with a cutaneous manifestation of erythema nodosum. CASE PRESENTATION We report the case of a 33-year-old Chinese woman with tuberculosis of the left breast accompanied by erythema nodosum on the anterior aspect of both lower legs. Due to he...

A 28 year old non smoker male with Behçet syndrome presented recurrent oral genital ulcers and erythema nodosum, giant pulmonary arterial saccular aneurysms (Figure 1 D) hemoptysis a nodule biopsy suggestive of necrotizing vasculitis.

Based on associated material collected from Macau and Guangxi, the pupae and larvae of Polypedilum (Pentapedilum) nodosum Johannsen and P. (Tripodura) masudai Tokunaga are described completely for the first time. Both species are newly recorded from China. Characters for distinguishing the immature stage of these species from other allied Polypedilum species are noted. The previously recorded P...

A case of acute sarcoidosis associated with the simultaneous appearance of cutaneous leucocytoclastic vasculitis and erythema nodosum is reported. Circulating immune complexes were demonstrated and may have been important in the pathogenesis of both types of skin lesion.