(1) Continuous erythropoietin receptor activator (CERA) is a third-generation erythropoiesis stimulating agent (ESA). CERA is used to correct anemia and maintain hemoglobin levels in patients with renal (kidney) failure. CERA is administered either once every two weeks (to correct anemia) or once per month (to maintain hemoglobin levels). This offers a potential advantage over other ESAs that r...

PURPOSE The initiation of a pharmacist-managed clinic to ensure appropriate use of erythropoietin-stimulating agents (ESAs) at a Veterans Affairs medical center is described. SUMMARY A drug-use evaluation (DUE) in 2005 showed that ESA therapy met all of the institution's usage criteria in only 2 of 49 patients receiving ESAs. A protocol was developed and approved for pharmacist management of ...

Sustained release of methane (CH(4)) to the atmosphere from thawing Arctic permafrost may be a positive and significant feedback to climate warming. Atmospheric venting of CH(4) from the East Siberian Arctic Shelf (ESAS) was recently reported to be on par with flux from the Arctic tundra; however, the future scale of these releases remains unclear. Here, based on results of our latest observati...

Acupunct Med 2011;29:173–179. doi:10.1136/aim.2011.004044 173 Abstract Purpose A pilot study to document changes in symptoms after acupuncture or nurse-led supportive care in patients with incurable cancer. Methods Patients receiving palliative care with estimated survival of at least 3 months were screened with the Edmonton Symptom Assessment System (ESAS). Patients (n=20) with signifi cant sy...

Tumor hypoxia, mostly resulting from poor perfusion and anemia, is one of the key factors in inducing the development of cell clones with an aggressive and treatment-resistant phenotype that leads to rapid progression and poor prognosis. Studies in patients with solid tumors suggest that there is a range of hemoglobin (Hb) concentrations that is optimum for tumor oxygenation. When used to achie...

BACKGROUND The literature supporting the use of music therapy in palliative care is growing. However, the number of quantitative research studies investigating the use of music therapy in palliative care, and specifically anxiety, is limited. OBJECTIVE The aim of this research project was to examine the effectiveness of a single music therapy session in reducing anxiety for terminally ill pat...

Since its advent in international affairs the 1990s concept of human security has been subject to a great interest within academia and political milieus. Various conceptions it were advanced received concrete forms. This paper is contribution both understanding sense satisfaction related society. Precisely from an essentialist perspective, advances naturalistic conception security, which enable...

Brief symptom instruments are designed to assess symptoms while maintaining low respondent burden, but they may omit important information. Our objective was to determine whether a representative brief symptom instrument effectively captures the full symptom experience of older adults with advanced diseases. In this cross-sectional study, we interviewed 90 community-dwelling adults with cancer,...

Chronic kidney disease (CKD) is the gradual, progressive deterioration of kidney function, and a condition that affects an estimated 26 million American adults. A common complication of CKD is anemia, which results from inadequate erythropoietin or from iron deficiency as a result of inadequate absorption or mobilization. The management of anemia in CKD patients must strike an appropriate balan...