Human skin heals more slowly in aged vs. young adults, but the mechanism for this delay is unclear. In humans, eccrine sweat glands (ESGs) and hair follicles underlying wounds generate cohesive keratinocyte outgrowths that expand to form the new epidermis. Here, we compared the re-epithelialization of partial-thickness wounds created on the forearm of healthy young (< 40 yo) and aged (> 70 yo) ...

BACKGROUND Functional annotation of novel proteins is one of the central problems in bioinformatics. With the ever-increasing development of genome sequencing technologies, more and more sequence information is becoming available to analyze and annotate. To achieve fast and automatic function annotation, many computational (automated) function prediction (AFP) methods have been developed. To ob...

BACKGROUND Advancements in function prediction algorithms are enabling large scale computational annotation for newly sequenced genomes. With the increase in the number of functionally well characterized proteins it has been observed that there are many proteins involved in more than one function. These proteins characterized as moonlighting proteins show varied functional behavior depending on...

OBJECTIVE Sympathetic stimulation leads to a change in electrical skin impedance. So far it is unclear whether this effect can be used to measure the effects of anaesthetics during general anaesthesia. The aim of this prospective study is to determine the electrical skin impedance during induction of anaesthesia for coronary artery bypass surgery with fentanyl and etomidate. METHODS The elect...

Abstract We analyse environmental ratings and emissions scores for commercial airlines from several major environmental, social governance providers. Specifically, we investigate whether capture predict absolute carbon intensity levels, are consistent across This builds on existing literature by evaluating the predictive ability of over significantly longer periods than past studies, examining ...

This research compared ratings of task performance and contextual performance from three different sources: self, peer, and supervisor. Participants were service industry employees in the service industries in Yogyakarta, Indonesia. A Sample of 146 employees and 40 supervisors   from the service industries provided ratings of task performance and contextual performance. The results indicated th...

The article examines the processes developing in global economy, reflecting transition to environmental friendliness (E), social responsibility (S) and high-quality corporate governance (G) signifying transformation of financial market into format “sustainable financing”. purpose is systematization ideas about ESG sustainable finance. evolution ESG, reveals essence criteria investment decisions...

ESG ratings are closely linked to corporate resource allocation and overarching macroeconomic constituents. Nevertheless, there is a noticeable lack in the literature investigating interconnected relationship between growth of local government debt, underinvestment, ratings. This study aims investigate impact debt on underinvestment its subsequent effects performance. To achieve this goal, util...

This dissertation explores approaches to the satisfiability problem, focusing on local search methods. The research endeavours to better understand how and why some local search methods are effective. At the root of this understanding are a set of metrics that characterize the behaviour of local search methods. Based on this understanding, two new local search methods are proposed and tested, t...

We investigate the differential effect of COVID-19 shock on share prices firms with different levels ESG (environmental, social and governance) scores. Thereby, we analyse whether to what extent higher ratings provided insurance for investors in stocks those during this shock. focus our analysis European market, which investment plays a particularly important role. Using broad sample listed fir...