BACKGROUND Anesthetic and ischemic preconditioning share similar signal transduction pathways. The authors tested the hypothesis that the beta1-adrenergic signal transduction pathway mediates anesthetic and ischemic preconditioning in vivo. METHODS Pentobarbital-anesthetized (30 mg/kg) rabbits (n = 96) were instrumented for measurement of systemic hemodynamics and subjected to 30 min of coron...

We read the article entitled ‘‘The effect of esmolol on corrected-QT interval, corrected-QT interval dispersion changes seen during anesthesia induction in hypertensive patients taking an angiotensin-converting enzyme inhibitor’’ by Ceker et al. with interest.1 The authors investigated the effects of esmolol on the hemodynamic, correctedQT (QTc) interval and corrected-QT interval dispersion (QT...

normal 0 false false false en-us x-none fa microsoftinternetexplorer4 background : hypertension and tachycardia caused by tracheal intubation can be detrimental in hypertensive patients. this study was conducted in order to compare the effects of dexmedetomidine on hemodynamic response to tracheal intubation in hypertensive patients with esmolol and sufentanyl. methods : sixty hypertensive pati...

Aims and Objectives: The aim of the study was to compare effects intravenous esmolol intranasal nitroglycerine spray on attenuation extubation pressor response in terms hemodynamic parameters adverse effects, if any, either drug. Methods: This a randomized comparative conducted tertiary care medical college which 64 patients ASA Grade I with age between 18 60 years, including both males females...

Introduction A continuous infusion of the beta-blocker esmolol has recently been demonstrated to increase stroke volume without increasing norepinephrine dosage or impairing microcirculation in patients with septic shock [1]. In addition, a pre-existing oral therapy with beta-blockers was associated with a potential 28-day mortality survival benefit in septic patients [2]. The influence of a ne...

Thyroid storm is an uncommon but potentially life-threatening manifestation of hyperthyroidism. Mortality can be 30-60% in hospitalized patients unless appropriately treated by combined therapy. We report a case of a 25-year-old African American woman with past medical history of Graves disease and moderately persistent asthma who presented to the emergency department with signs and symptoms of...