BACKGROUND Because 24-h esophageal pH monitoring is quite invasive, the diagnosis of gastroesophageal reflux disease (GERD)-associated cough has usually been made based merely on the clinical efficacy of treatment with proton pump inhibitor (PPI). CASE PRESENTATION We recently encountered two patients with PPI-responsive chronic non-productive cough for whom switching from bronchodilators and...

AIM The aim of this study was to evaluate the epidemiology of GERD base on population study in Tehran providence. BACKGROUND Gastro-esophageal reflux disease (GERD) is a common and chronic problem. Recent reports from developing countries indicate increment in the incidence and prevalence of the disease over the past. PATIENTS AND METHODS This study was a cross-sectional household survey co...

Gastroesophageal reflux (GER), defined as the passage of gastric contents into the esophagus, is a physiologic process that occurs throughout the day in healthy infants and children. Gastroesophageal reflux disease (GERD) occurs when gastric contents flow back into the esophagus and produce symptoms. The most common esophageal symptoms are vomiting and regurgitation. Lifestyle changes are the f...

BACKGROUND The duration of gastro-esophageal reflux disease (GERD), the frequency of reflux, the pH and type of acid, and the quality and quantity of saliva affect the severity of dental erosion due to GERD. OBJECTIVE To summarize the diagnostic protocol and treatment of dental erosion due to GERD. METHODS A Medline literature search was performed to identify articles associated with a dent...

An association between obesity and symptoms of gastro-esophageal reflux disease (GERD) has been frequently reported in western societies. A recent study indicated a consistent association between abdominal diameter and reflux-type symptoms in the white population, but no consistent association in the black population or Asians. It is unclear whether an association persists after adjusting for k...

INTRODUCTION Recent studies have suggested that both laparoscopic and open anti-reflux surgery may produce regression of Barrett's mucosa. MATERIAL AND METHODS;: We reviewed 21 patients (13M: 8F, mean age 46.7±3.18 years) with documented Gastroesophageal Reflux Disease (GERD) and Non-dysplastic Barrett's esophagus (15 patients ?3 cm segment, 6 patients < 3 cm segment) on long term proton pump i...

Esophageal inflammation is the highly complex protective response to cellular/tissue injury, one of the fundamental features in gastroesophageal reflux disease (GERD) that represents a wide group of acidrelated disorders, where a majority of patients appear to have nonerosive reflux disease (NERD) with minimal change esophagitis and no endoscopic abnormalities. Despite recent advances and bette...

OBJECTIVES To review the literature on the treatment of gastroesophageal reflux disease (GERD) with emphasis on pharmacological aspects. To identify particularities of pharmacological treatment of esophageal and extraesophageal manifestations of the disease. SOURCES Electronic search of the PubMed/MEDLINE and Cochrane Collaboration databases. Controlled and randomized studies published since ...

Gastro-esophageal reflux disease (GERD) is “a condition which develops when the reflux of stomach contents causes troublesome symptoms (i.e., at least two heartburn episodes per week) and/or complications” (Vakil et al 2006) and represents one of the fastest growing disease affecting the alimentary tract. Recently studies on the epidemiology of GERD demonstrating that GERD is a highly prevalent...

OBJECTIVES The aim of this study was to assess the clinical utility of esophageal manometry among Sudanese patients presenting to the National Centre for Gastrointestinal and Liver Diseases, Ibn Sina Hospital, Khartoum, Sudan. METHODOLOGY Consecutive patients referred for esophageal manometry at the aforementioned center from July 2008 through January 2011 were included in the study. Manometr...