Ninety hypertensive patients were investigated by intravenous pyelography, abdominal aortography, and renal biopsy. Accessory arteries were present in four of thirty-nine patients with secondary hypertension, whereas sixteen of fifty-one patients with primary hypertension exhibited this anomaly. These differences in distribution are statistically significant, and the relationship between access...

A substantial proportion of patients with hypertension have a low or suppressed renin. This phenotype of low-renin hypertension (LRH) may be the manifestation of inherited genetic syndromes, acquired somatic mutations, or environmental exposures. Activation of the mineralocorticoid receptor is a common final mechanism for the development of LRH. Classically, the individual causes of LRH have be...

Plasma vasopressin levels were compared in three groups comprising normotensive, mildly hypertensive, and more severely hypertensive patients, both under basal conditions and following an 85 degrees head-up tilt, a stimulus known to provoke vasopressin release in man. Vasopressin levels increased two- to fivefold in all subjects after tilt; however, neither the basal levels nor the maximal leve...

UNLABELLED The present study shows the results of monitoring, evaluation and prediction of health status in a patient group with hypertension (HTN) seeking care in a permanent medical center. MATERIALS AND METHODS The study evaluated 144 patients registered at the Permanent Medical Center of the Plugari village, Iaşi County, who were diagnosed with HTN between 2011 and 2013. The study group i...

OBJECTIVE To compare blood pressure control, satisfaction, and adherence to drug treatment in patients with treated hypertension followed up by their family physicians either every three months or every six months for three years. DESIGN Randomised equivalence clinical trial. Settings 50 family practices in south eastern Ontario, Canada. PARTICIPANTS 609 patients aged 30-74 years with essen...

Essential (primary) hypertension is an important risk factor for cardiovascular morbidity and mortality. Blood pressure is largely heritable; however, the genetic factors contributing to essential hypertension are mostly unknown. We examined a large Chinese kindred (n=387) and selected a subset of 94 individuals for genotyping. An additional 32 Chinese nuclear families with essential hypertensi...

Ann Intern Med. www.annals.org For author affiliation, see end of text. * The article appeared simultaneously in Annals of Internal Medicine and Pediatrics. Readers who wish to cite the article should use the following citation: Moyer VA, U.S. Preventive Services Task Force. Screening for primary hypertension in children and adolescents: U.S. Preventive Services Task Force recommendation statem...

A 53-year-old male was referred to our Department for refractory primary hypertension. Despite high doses of 6 anti-hypertensive drugs, ambulatory monitoring of blood pressure (BP) revealed a mean BP of 160/90 mmHg. Under local anaesthesia, renal denervation with radiofrequency was performed supported by high-resolution 3D angiography, which helped confirm the position of the applications in a ...

Essential hypertension, which accounts for 90%-95% of all cases of hypertension seen in the clinic, is also referred to as idiopathic hypertension, because we simply don't understand the cause(s). Although many theories have been advanced, in the current issue of the JCI, Gonzalez-Villalobos et al. present further evidence implicating the intrarenal renin-angiotensin system and take us one step...

A,N IMPERFECT UNDERSTANDING of the relationship between the level of arterial blood pressure and the development of hypertensive complications is one of the conspicuous difficulties in current concepts of the natural history of essential hypertension. That cardiovascular complications of hypertension are generally more prevalent with the higher levels of blood pressure is recognized. Published ...