Tuberculosis is more sophisticated to diagnose in pregnant women contract the diseases because tuberculosis clinical manifestations suchlike tiredness, difficulty of breathing, sweating, weakness, coughing, and rare body temperature that higher than normal are identical physiology changed during pregnancy. According United States food drug administration risk classification medicines among preg...

Polyamines protected Mycobacterium smegmatis from ethambutol inhibition but not from streptomycin inhibition, whereas MgSO(4) neutralized growth inhibition by both drugs.

The reliability of the MB/BACT system for susceptibility testing of Mycobacterium tuberculosis to pyrazinamide, rifampin, isoniazid, streptomycin, and ethambutol was compared to the BACTEC 460TB system. The proportion method was used to resolve discrepant results by an independent arbiter. Two interpretative methods were used, with an undiluted control (direct control) and a diluted control (10...

Abstract Tuberculosis continues to wreak havoc worldwide and caused around 1.4 million deaths in 2019. Hence, our pursuit of developing novel antitubercular compounds, we are reporting the e-Pharmacophore-based design DprE1 (decaprenylphosphoryl-ribose 2′-oxidase) inhibitors. In present work, have developed a four-feature e-Pharmacophore model based on receptor–ligand cavity protein (PDB ID 4P8...