RUNX1 is a transcription factor that regulates critical processes in many aspects of hematopoiesis. RUNX1 is also integral in defining the definitive hematopoietic stem cell. In addition, many hematological diseases like myelodysplastic syndrome and myeloproliferative neoplasms have been associated with mutations in RUNX1. Located on chromosomal 21, the RUNX1 gene is involved in many forms of c...

The characteristics of Engineer to Order (ETO) companies are described in terms of their markets, products and the internal processes of their organisation. These are set in the context of current trends in supply chain management. The business processes associated with the procurement and marketing functions and the interactions with other processes are analysed. These are compared for a numbe...

BACKGROUND & OBJECTIVES Increase in the isolation of drug resistant phenotypes of Mycobacterium tuberculosis necessitates accuracy in the testing methodology. Critical concentration defining resistance for ethionamide (ETO), needs re-evaluation in accordance with the current scenario. Thus, re-evaluation of conventional minimum inhibitory concentration (MIC) and proportion sensitivity testing (...

The fusion transcript AML1/ETO was detected in the bone marrow of two t(8;21)-negative acute myelogenous leukemia (AML) patients by means of reverse transcription-polymerase chain reaction. This fusion transcript is identical to the one transcribed from the t(8;21) translocation base, as deduced from (a) the size and restriction pattern of the amplified DNA fragment and (b) the DNA sequence ana...

Com a escassez de informações na literatura sobre irrigação no cultivo da pitaya em região Semiárido Pernambucano, este trabalho tem como objetivo avaliar as características físico-químicas duas variedades pitaya, resposta à aplicação diferentes lâminas irrigação, baseados percentuais evapotranspiração referência (ETo). Foi utilizado o delineamento blocos casualizados, com os tratamentos arranj...

In this paper, optimum trajectories in Earth Transfer Orbit (ETO) for a lunar transportation system are proposed. This paper aims at improving the payload ratio of the reusable orbital transfer vehicle (OTV), which transports the payload from Low Earth Orbit (LEO) to Lunar Low Orbit (LLO) and returns to LEO. In ETO, we discuss ballistic flight using chemical propulsion, multi-impulse flight usi...

The effects of different concentrations of etoposide and cycloheximide (ETO-CHXM), used for chemical enucleation of mouse oocytes, on polar body extrusion and chromatin expulsion were tested. The developmental ability of blastomeres of late 2-cell stage embryos fused to chemically enucleated oocytes of different ages or cytoplasts from different sources was also examined in vitro. Metaphase I o...

The water availability in soil strongly influences crop growth by sustaining photosynthesis, respiration, and the maintenance of plant temperature. will decrease due to evapotranspiration (ETc) which is influenced reference (ETo) coefficient (Kc). During shortage, Kc evaporation (Ke) basal (Kcb) can be calculated using Blue Red Vegetation Index (BRVI). purpose this study was apply evaluate a ne...