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BACKGROUND To identify potential causes and clinical implications of transient increases in plasma viral load (hereafter, "blips"). METHODS M99-056 and M02-418 were prospective, randomized trials evaluating the safety and efficacy of lopinavir/ritonavir (LPV/r) capsules administered twice per day or once per day to subjects infected with human immunodeficiency virus-1 (HIV-1). Plasma viral lo...
Background: For nearly 100 years, amniotic membranes have been used to treat various types of skin wounds. Amniotic extract is one of the derivatives of amniotic membrane that contains all the properties of amniotic membrane. The aim of this study was to evaluate the safety of the amniotic membrane extract in the treatment of diabetic ulcers. Methods: This study was an Open labeled clinical tr...
In this paper, we study the class of rings in which every $P$-flat ideal is flat and which will be called $PFF$-rings. In particular, Von Neumann regular rings, hereditary rings, semi-hereditary ring, PID and arithmetical rings are examples of $PFF$-rings. In the context domain, this notion coincide with Pr"{u}fer domain. We provide necessary and sufficient conditions for...
AIM The REbif FLEXible dosing in early MS (REFLEX) study compared several brain MRI outcomes in patients presenting with clinically isolated syndromes suggestive of multiple sclerosis and treated with two dose-frequencies of subcutaneous interferon (IFN) β-1a or placebo. METHODS Patients were randomised (1:1:1) to IFN β-1a, 44 µg subcutaneously three times a week or once a week, or placebo th...
BACKGROUND The purpose of this study was to examine whether the frequency of breakfast consumption was related to academic performance in healthy Korean adolescents. METHODS We analyzed data from the seventh Korea Youth Risk Behavior Web-based Survey conducted in 2011, in which 75,643 adolescents from school grades 7-12 participated. We assessed the association between the frequency of breakf...
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