نتایج جستجو برای: expanded disability status scale scores edss
تعداد نتایج: 1178332 فیلتر نتایج به سال:
Patients with autoimmune disorders often have low levels of 25-hydroxyvitamin D [25(OH)D3], which correlates with disability or disease activity. Vitamin D may play a role in neuromyelitis optica (NMO) or NMO spectrum disorder (NMOSD), as an important factor involved in immunological pathways. We investigated the relationship between vitamin D levels and disease related disability and clinical ...
conclusions these results suggest that treadmill training and yoga practice improved ambulatory function, fatigue and mood status in the individuals with mild to moderate ms. patients and methods thirty-one ms patients, all female with mean of age of 36.75 years and expanded disability status scale scores (edss) of 1.0 to 4.0 were recruited. subjects were randomly assigned to one of the three g...
Improvement to baseline after plasma exchange in spinal attacks associated with neuromyelitis optica
The article by Abboud et al. investigating the outcome of neuromyelitis optica (NMO) relapses treated by steroids alone or in association with plasma exchange (PLEX) demonstrates a better outcome in PLEX-treated attacks with a higher proportion of patients improving to baseline Expanded Disability Status Scale (EDSS): 65% vs 35%. Considering the high level of significance of their results, they...
BACKGROUND Chronic cerebrospinal venous insufficiency (CCSVI) is a vascular condition characterized by anomalies of the primary veins outside the skull that has been reported to be associated with MS. In the blinded Combined Transcranial (TCD) and Extracranial Venous Doppler Evaluation (CTEVD) study, we found that prevalence of CCSVI was significantly higher in multiple sclerosis (MS) vs. healt...
OBJECTIVES We conducted a prospective study, MSBASIS, to assess factors leading to first treatment discontinuation in patients with a clinically isolated syndrome (CIS) and early relapsing-remitting multiple sclerosis (RRMS). METHODS The MSBASIS Study, conducted by MSBase Study Group members, enrols patients seen from CIS onset, reporting baseline demographics, cerebral magnetic resonance ima...
BACKGROUND To determine which short-term changes on clinical scales including the Expanded Disability Status Scale (EDSS), Timed 25-Foot Walk (T25FW), 9-Hole Peg test (9HPT) and Guy's Neurological Disability Scale (GNDS) are most predictive of long-term outcome of disability as rated by the EDSS in progressive multiple sclerosis (MS). METHODS From a longitudinal database, all progressive pati...
Background: Multiple sclerosis (MS) is an inflammatory and demyelinating disease of central nervous system (CNS). The aim of the present study was to determine the type and the frequency of initial presenting symptoms in patients with MS and their relation with demographic characteristics in Babol, northern Iran. Methods: All patients of this study were recruited over a ten year period fr...
Abstract Multiple sclerosis (MS) patients with immunoglobulin gamma (IgG) oligoclonal bands (OCB) in the cerebrospinal fluid (CSF) have different genetic backgrounds and brain MRI features compared to those without. In this study, we aimed determine whether CSF-OCB status is associated long-term disability outcomes. We used Swedish MS register data on clinically definite known OCB status. Date ...
METHOD A systematic review of the literature from 1990 to 2011 was conducted. Outcome measures included: mean cost of disease modifying therapies (DMTs), mean cost of treatment of relapses and mean cost of disease by stage stratification measured by the expanded disability status scale (EDSS). RESULTS Seven studies from three countries (Brazil, Argentina and Colombia) were included. In 2004, ...
Background: Mesenchymal stem cells (MSCs) with their potential to differentiate into mesodermal and non-mesodermal lineages have several immunomodulatory characteris-tics. These properties make them promising tools in cell and gene therapy. Objective: To evaluate the potential therapeutic applications of autologous MSC in improving clinical manifestations of MS patients. Methods: Ten patients w...
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