The amino acid sequences at the "proteolytic processing regions" of cathepsin Ds have been determined for the enzymes from cows, pigs, and rats in order to deduce the sites of cleavage as well as the function of the proteolytic processing of cathepsin D. For bovine cathepsin D, the "processing region" sequence was determined from a peptide isolated from the single-chain enzyme. The COOH-termina...

Abstract We consider the Euler characteristics $\chi (M)$ of closed, orientable, topological $2n$ -manifolds with $(n-1)$ -connected universal cover and a given fundamental group G type $F_n$ . define $q_{2n}(G)$ , generalised version Hausmann-Weinberger invariant [19] for 4–manifolds, as minimal value $(-1)^n\chi For all $n\geq 2$ we establish strengthened extended their estimates, in terms ex...

For δ ≥ 1 and n ≥ 1, we examine the simplicial complex of graphs on n vertices in which each vertex has degree at most δ; we identify a given graph with its edge set and admit one loop at each vertex. δ = 1 yields the matching complex, and it is known that there is 3-torsion in degree d of the homology of this complex whenever n−4 3 ≤ d ≤ n−6 2 . We establish similar bounds for δ ≥ 2. Specifica...

We extend superspace by introducing an antissymetric tensorial coordinate and develop the corresponding extended supersymmetric invariant theory. After integrating over the tensorial coordinate, an effective action describing massive bosons and fermions is explicitely derived for the spacetime dimension D = 2. The adopted procedure is simpler than the Kaluza-Klein one and can suggest an alterna...

In this article, we study how the Grothendieck group of coherent sheaves can be used to describe D-branes. We show how global bound state construction in topological K-theory can be adapted to our context, showing that D-branes wrapping a subvariety are holomorphically classified by a relative K-group. By taking the duality between the relative K-groups and the K-homologies, we show that D-bran...

dirofilaria immitis is an important filarial nematode in dogs. in this study, age and sex distribution of this zoonotic nematode among dogs were investigated in northwest of iran in meshkin-shahr city. molecular characteristics of the isolates, based on cytochrome oxidase subunit 1 (cox1) gene were compared to the isolates from other areas of the world.blood samples were collected from 91 dogs ...