This work presents the validation study of comprehensive two-dimensional gas chromatography-time of flight mass spectrometry (GC×GC-TOFMS) method performance in analysis of the key WADA anabolic agents in doping control. The relative abundance ratio, retention time, identification and other method performance criteria have been tested in the GC×GC format to confirm if they comply with those set...

The ethyl acetate-based multi-residue method for determination of pesticide residues in produce has been modified for gas chromatographic (GC) analysis by implementation of dispersive solid-phase extraction (using primary-secondary amine and graphitized carbon black) and large-volume (20 muL) injection. The same extract, before clean-up and after a change of solvent, was also analyzed by liquid...

Objective: This study was to develop the first simultaneous method for quantification of MI and MCI by using matrix solid-phase dispersion (MSPD) as an extraction technique followed gas chromatography-tandem mass spectrometry (GC-MS) in cosmetic products support that law enforcement.
 Methods: The were extracted from sample with alumina solid sorbent ethyl acetate eluent. After being isola...

Subtype-selective thyromimetics have potential as new pharmaceuticals for the prevention or treatment of heart disease, high LDL cholesterol and obesity, but there are only a few methods that can detect agonistic behavior of TR-active compounds. Among these are the rat pituitary GH3 cell assay and transcriptional activation assays in engineered yeast and mammalian cells. We report the construct...

The current study applied gas chromatography-mass spectrometry (GC–MS), liquid (LC-MS), and thermal desorption direct analysis in real-time mass (TD-DART-MS) methods to the of black pepper (Piper nigrum L.) samples from different countries. powder were analyzed directly by TD-DART-MS without any extraction, but for GC–MS LC-MS methods, a methanol extraction procedure was employed before analysi...

Whole genome amplification (WGA) offers a means to enrich DNA quantities for epidemiologic studies. We used an ovarian cancer study of 1,536 single nucleotide polymorphisms (SNPs) and 2,368 samples to assess performance of multiple displacement amplification (MDA) WGA using an Illumina GoldenGate BeadArray. Initial screening revealed successful genotyping for 93.4% of WGA samples and 99.3% of g...

BACKGROUND Various factors may affect the clinical prognosis of lymph node-negative gastric cancer (GC) patients. This study aimed to provide evaluable prognostic information of combination of tumor size (Ts), lymph nodes count (LNs) and lymphovascular invasion (LVI) in lymph node-negative GC patients. METHODS A total of 1,019 node-negative GC patients were enrolled in this retrospective stud...

in order to determine aqueous extract effects of cool-season turfgrass mixture clipping on germination and seedling growth of four weed species, laboratory and outdoor pot experiments were done at the experimental laboratory and greenhouse of the doroud parks and landscape organization, located in doroud, lorestan, iran. the first factor was the concentration of sport turfgrass clipping extract...

fungi produce a wide range of secondary metabolites such as antibiotics, toxins, alkaloids, fatty acids, ketones and alcohols during active cell growth. the present study was aimed to identify secondary metabolites from some penicillium species, using gc-ms. many important compounds such as 3-oxoquinuclidine in penicillium jenseii, formamidine in penicillium pusillum, orcinol and 1,3,8-p-mentha...