Increasing energy and housing demands are impacting wildlife populations throughout western North America. Greater sage-grouse (Centrocercus urophasianus), a species known for its sensitivity to landscape-scale disturbance, inhabits the same low elevation sage-steppe in which much of this development is occurring. Wyoming has committed to maintain sage-grouse populations through conservation ea...

BACKGROUND Gallbladder cancer (GBC) is an uncommon neoplasm in the United States, but one with high mortality rates. This malignancy remains largely understudied at the molecular level such that few targeted therapies or predictive biomarkers exist. EXPERIMENTAL DESIGN We built the first series of serial analysis of gene expression (SAGE) libraries from GBC and nonneoplastic gallbladder mucos...

Declines in greater sage grouse (Centrocercus urophasianus) productivity and population numbers throughout their range demand a better understanding of how nutrition influences sage grouse populations. During March and April 1999-2001, blood samples were collected from 158 female (73 adult, 85 yearling), free-ranging, prelaying, greater sage grouse from an area in northwestern Nevada, USA, and ...

Professor of Geography, University of California, Los Angeles, California 90024 USA Abstract: Unlike chaparral, shrubs of coastal sage are capable of continual seedling reproduction. As a result, mixed-aged stands form which show little senescence. Litter turnover is twice as rapid. The more open sage scrub canopy permits persistence of a diverse herb layer into mature communities. Crown sprout...

Despite a wide array of safe and effective vaccines in use globally, with major impacts on health worldwide, the WHO Strategic Advisory Group of Experts (SAGE) on Immunization has been repeatedly confronted with reports of hesitancy towards accepting specific vaccines or vaccination programmes. This paper summarizes the rationale for a SAGE review of the issue of vaccine hesitancy, its impact a...

With the emergence of inexpensive commercial off-the-shelf (COTS) parts, heterogeneous multi-processor HPC platforms have now become more affordable. However, the effort required in developing real-time applications that require high-performance and high input/output bandwidth for the HPC systems is still difficult. Honeywell Inc. has released a suite of tools called the Systems and Application...

A method is reported for enhancing the sensitivity of NMR of dissolved xenon by detecting the signal after extraction to the gas phase. We demonstrate hyperpolarized xenon signal amplification by gas extraction (Hyper-SAGE) in both NMR spectra and magnetic resonance images with time-of-flight information. Hyper-SAGE takes advantage of a change in physical phase to increase the density of polari...

To profit in today’s market, small manufacturers must be efficient and agile to minimise cost and to meet variable market demand. This paper discusses an envisaged Semantic, Ambient, Generic and Extensible framework (SAGE) focused on the manufacturing environment. SAGE is based on the ambient intelligence philosophy which means it is focused on the human actor with the aim of aiding them to opt...

The potential of the SAGE (Space Alternating Generalized Expectation Maximization) algorithm for navigation systems in order to distinguish the line-of-sight signal (LOSS) is to be considered. The SAGE algorithm is a low-complexity generalization of the EM (Expectation-Maximization) algorithm, which iteratively approximates the maximum likelihood estimator (MLE) and has been successfully applie...

We present a computer program, termed V-SAGE (Virtual-SAGE), designed to facilitate the analysis of gene expression profiles by combining elements of SAGE (Serial Analysis of Gene Expression) with high-throughput EST analysis. The program re-iteratively correlates sequence tags adjacent to poly(A) tail sequence strings with a second or several tags located within the cDNA adjacent to the recogn...