BACKGROUND Theories provide a synthesizing architecture for implementation science. The underuse, superficial use, and misuse of theories pose a substantial scientific challenge for implementation science and may relate to challenges in selecting from the many theories in the field. Implementation scientists may benefit from guidance for selecting a theory for a specific study or project. Under...

On other occasions I have argued that ‘informal logic’ should not really be seen as a kind of ‘weak’ form of logic, but rather as ‘applied epistemology.’ This categorization is intended to create an analogy with applied ethics. Applied ethics has created a robust research project and stimulated ethical thinking both in and outside philosophy. As with applied ethics, I believe that as philosophe...

Though it has had an immense influence outside of philosophy, the thought of Karl Popper continues to be neglected and misunderstood by most professional philosophers. Nor do we need to look far for an explanation of the fact that Popper's philosophy has received more serious attention from social theorists, working scientists, historians of art, and practicing politicians, for example, than fr...

In ‘Epistemology and ethics of evidence-based medicine: Putting goal-setting in the right place’, Piersante Sestini argues that evidence-based medicine (EBM) is highly consistent with Karl Popper’s philosophy of science, which famously demarcated science by the falsifiability criterion and highlighted for generations of scientists the inherent fallibility of scientific claims. In this commentar...

We review the development of renormalizable SO(10) Susy GUTs based on the 210 ⊕⊕126 ⊕ 126 ⊕ 10 Higgs system. These GUTs are minimal by parameter counting. Using the SO(10) → SU(4) × SU(2)L × SU(2)R label decomposition developed by us we calculated the complete GUT scale spectra and couplings and the threshold effects therefrom. The corrections to αG, Sin θW and MX are sensitive functions of the...

Once upon a time validation of robotic research was relatively straightforward. Let us assume, for example, that a researcher had published in a journal a novel adaptive control law with a numerical example on a two-link robot. Beyond the formal proof of convergence, he supplied to the reader the differential equations used to model the system, including the corresponding dynamic parameters (no...

?Computer simulations are useful because they can characterize the expected performance of phylogenetic methods under idealized conditions. However, simulation studies are also subject to several sources of bias that make the results of different simulation studies difficult to interpret and often contradictory. In this study, I examined the performance of 26 commonly used methods of phy? logen...

TO THE EDITOR: We are grateful to our colleagues for their comments (see Ref. 1) about the proposed model of local blood flow regulation (3). The two main objections put forward are its simplicity and its incompatibility with conventional belief in the “highly complex nature” and “substantial redundancy” of flow control. Interactions between physiological systems are typically implemented throu...

Наука как познание – это процесс. социальная система тоже В этих процессах мы время от времени фиксируем опорные точки, позволяющие описывать их с точки зрения определенной универсальной позиции. том числе, я полагаю, на роль такой позиции подходит представление об ориентации в окружающей среде. Познание и сопутствующая ему наука таком случае предстают все более сложной ориентации, сложность ко...

In their 2004 Trends in Cognitive Sciences review of inhibition and the right inferior frontal cortex (rIFC), Aron et al. (henceforth AR&P) boldly claimed that “inhibition is localized to right IFG alone” (Aron et al., 2004). Ten years later, the authors have updated their theory to include one or more fronto–basal–ganglia networks along with rIFC, and to characterize the function of rIFC as a ...