Nodular lung disease is a rare pulmonary manifestation of sarcoidosis and resembles metastatic neoplasm disease. Nodular sarcoidosis is rare, varying from 1.6% to 4% of patients with sarcoidosis. Radiographic nodules measure from 1 to 5 cm in diameter that typically consist of coalescent granulomas. There is limited data on this form of sarcoidosis and its presentation can mimic primary or meta...

Clinical changes of lacrimal gland (LG) in sarcoidosis are studied. 33 patients (66 orbits) with verified systemic sarcoidosis were examined using digital ultrasound. Different varieties of LG structural changes in sarcoidosis are studied. Different types of LG structural changes were determined in patients with sarcoidosis defined as pseudoedematous and combined forms. Analysis of the results ...

Gastrointestinal (GI) sarcoidosis is a very rare disease, which clinically presents along with systemic disease or as an isolated finding. Gastric sarcoidosis is the most common form of GI sarcoidosis. Symptomatic gastric sarcoidosis is rare and only few case reports have been described in the literature with well-documented histological evidence of noncaseating granulomas. We present an intere...

Sarcoidosis is a multisystemic granulomatous disease of unknown aetiology that usually presents with bilateral hiliar adenopathies, pulmonary infiltrations, and ocular and cutaneous lesions. The specific cutaneous lesions, or granulomatous, are produced in from 9% to 37% of patients with systemic sarcoidosis. Nevertheless, few patients have been described having specific lesions from sarcoidosi...

Here, we describe a case of colonic sarcoidosis that developed over a 7-year period of observation of intrathoracic sarcoidosis. The patient was asymptomatic, but colonoscopy showed multiple elevated lesions mimicking submucosal tumors in several areas of the colon. The specimens obtained by biopsy showed noncaseating granuloma, suggesting sarcoidosis. The observations in the present case indic...

References CHAPMAN, J.S. (1955) Note on the secondary factors involved in the etiology of sarcoidosis. American Review of Tuberculosis, 71, 459. COLOVER, J. (1948) Sarcoidosis with involvement of the nervous system. Brain, 71, 451. DA COSTA, J.L. (1973) Geographic epidemiology of sarcoidosis in South East Asia. American Review of Respiratory Disease, 108, 1269. HSING, C.T. (1964) Sarcoidosis am...

Rationale: Management of sarcoidosis patients with the potential for multi-organ involvement can be complex and require the expertise of multiple specialties. Objectives: Our goal was to estimate the current number of clinics dedicated to the management of patients with sarcoidosis, and to evaluate what clinic structures and definitions currently exist. Methods: A link to an online survey was e...

BACKGROUND Cases of tattoo sarcoidosis reported in English and French literature have recently been reviewed; however, only two Japanese patients were included in the review because most Japanese patients were reported in Japanese journals. OBJECTIVES To determine the clinical characteristics of Japanese tattoo sarcoidosis. METHODS We reported a Japanese female with tattoo sarcoidosis, and ...

BACKGROUND In recent years we have observed with increasing frequency granulomatous papular lesions involving the knees, for which we proposed the term papular sarcoidosis of knees. OBJECTIVES To evaluate the clinicopathological features of papular sarcoidosis of the knees. METHODS Patients with papular lesions of the knees and histopathologically sarcoid granulomas were included in the stu...

OBJECTIVE Sarcoidosis is a systemic inflammatory disorder characterized by granulomas. Although the aetiology is unknown, sarcoidosis is thought to be mediated by Th1 lymphocytes. Recently, IL-17A has been implicated in granuloma formation in various diseases, including tuberculosis. Therefore, we hypothesized that Th17 cells play a role in sarcoidosis, paralleling recent findings in autoimmune...