holt-oram syndrome (hos) is a developmental disorder inherited in an autosomal-dominant pattern. affected organs are the heart and forelimbs with upper extremity skeletal defects and congenital heart malformation. in this study we present three cases of hos in the same family. in one of these three individuals we detected a transition of c to t (ctg-gtt, v205v) in exon 7 of the tbx5 gene. this ...

by reducing the growth rate and aging population countries, communities population has become a controversial issue. this subject has led many thinkers to understand the factors influencing fertility decline. understanding the quality of fertility reduction and family change requires to understand the status of women which is a result of global changes. because women as one of the pillars of th...