نتایج جستجو برای: farber disease
تعداد نتایج: 1490893 فیلتر نتایج به سال:
From the Dana–Farber Cancer Institute, Harvard Medical School, Boston (P.W.K.); School of Medicine, University of Washington, Seattle Cancer Care Alliance, Seattle (C.S.H.); Carolina Urologic Research Center, Myrtle Beach, SC (N.D.S.); School of Medicine, SUNY at Stony Brook, Stony Brook, NY (E.R.B.); Urologic Oncology Program, University of California San Francisco, San Francisco (E.J.S.); Van...
When the Oncology Nursing Society (ONS) was almost exactly half its present age, in November 1994, a Boston Globe health columnist named Betsy Lehman was admitted to the Dana-Farber Cancer Institute in Boston, Massachusetts, to receive an investigational regimen for breast cancer. Her treatment ended in disaster. In one of the most notorious patient safety failures of modern times, Lehman was g...
Recently, intensive laboratory and preclinical studies have identified and validated therapeutic molecular targets in multiple myeloma (MM). The introduction of novel agents such as the proteasome inhibitor bortezomib and the immunomodulatory drugs thalidomide and lenalidomide, which were rapidly translated from preclinical studies at the Dana-Farber Cancer Institute into clinical trials, has c...
1James P. Wilmot Cancer Center, University of Rochester, NY; 2Stanford University, CA; 3Cleveland Clinic, OH; 4Mayo Clinic, Rochester, MN; 5University of Nebraska, Omaha; 6Dana-Farber Cancer Institute, Boston, MA; 7University of California at Los Angeles; 8Emory University, Atlanta, GA; 9Cornell University, New York, NY; 10Indiana University, Indianapolis; 11Rush University, Chicago, IL; and 12...
The Golgi apparatus consists of disc-like cisternae, stretching around the nucleus through forces exerted by F-actin and the Golgi membrane protein GOLPH3. Farber-Katz et al. now report that DNA damage triggers Golgi dispersal and inhibits vesicular transport through DNA-PK-mediated GOLPH3 phosphorylation, thereby linking the DNA damage response to Golgi regulation.
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