We have used a continuous intravenous infusion of glucose (6 mg/kg/min), insulin (80 mU/min), epinephrine (6 mug/min), and propranolol (0.08 mg/min) to directly assess insulin resistance in 14 untreated adult onset diabetics with a mean (plus or minus SE) fasting plasma glucose level of 217 plus or minus 17 mg/100 ml. During the infusion endogenous insulin secretion is inhibited and steady-stat...

OBJECTIVE To evaluate whether nocturnal asymptomatic hypoglycemia (NAH) can be predicted by fasting glucose levels or post-breakfast glucose fluctuations in patients with type 1 diabetes (T1D) receiving insulin degludec. METHODS Patients with T1D receiving insulin degludec underwent at-home CGM assessments. Indices for glycemic variability before and after breakfast included fasting glucose l...

Plasma is the most patronized sample for the assay of glucose utilized as a focal biomedical marker for the diagnosis of diabetes mellitus. The procedure is painful and the cost implication is huge. Hence, the need for an alternative non-invasive sample void of painful sensation and of cheap cost implication is pertinent. In this study a total of 100 subjects were utilized and divided into two ...

background: saffron is the dried stigmata of the flowers of saffron (crocus sativus l., iridaceae). saffron and its major active constituents, crocin (crocetin glycoside), crocetin and safranal, have a variety of pharmacological effects including high antioxidant properties and crocetin has insulin sensitizing effect possibly due to its antioxidant activity. oral crocin is not absorbed and is h...

Glucose levels in 154 random specimens of lumbar cerebrospinal fluid, normal as regards cell and protein content, were estimated by the glucose-oxidase method and a mean value of 60.5 mg./100 ml. (S.D. 7.3) was obtained. In 33 fasting patients subject to air encephalography the mean cerebrospinal fluid (C.S.F.) glucose level was 56.5 mg., and mean blood glucose level 65.5 mg. with an average C....

BACKGROUND It is not clear whether elevated uric acid is a risk factor for the onset of impaired fasting glucose after stratifying by baseline fasting plasma glucose levels. We conducted a community-based retrospective longitudinal cohort study to clarify the relationship between uric acid levels and the onset of impaired fasting glucose, according to baseline fasting plasma glucose levels. M...

OBJECTIVE To compare the fasting blood glucose (FBG) level in the healthy young individuals with diabetic first degree relatives considered as high risk and non-diabetic first degree relative considered as low risk. STUDY DESIGN Cross-sectional, comparative study. PLACE AND DURATION OF STUDY Department of Medicine, Liaquat University of Medical and Health Sciences Hospital, Hyderabad/Jamsho...

AIMS To evaluate whether fasting plasma glucose values measured early during insulin therapy can identify patients with Type 2 diabetes who may not achieve adequate glycaemic control after 6 months and will require additional treatment. METHODS Patient-level data from seven prospective, randomized, controlled studies using treat-to-target methods were pooled to evaluate the efficacy of insuli...