The effect of arbidol and its structural analogues on the process of lipid peroxidation in phospholipid liposomes induced by Fe2+ has been investigated. It was shown that the antioxidant efficacy of arbidol and its derivatives is lower than that of alpha-tocopherol by two or three times. It was suggested that the mechanism antioxidant action of the arbidol and its structural analogues consists ...

The ability of a benzoquinonoid bridging ligand to mediate double-exchange coupling in a mixed-valence Fe2 complex is demonstrated. Metalation of the bridging ligand 2,5-di(2,6-dimethylanilino)-3,6-dibromo-1,4-benzoquinone (LH2) with Fe(II) in the presence of the capping ligand tris((6-methyl-2-pyridyl)methyl)amine (Me3TPyA) affords the dinuclear complex [(Me3TPyA)2Fe(II)2(L)](2+). The dc magne...

[Fe2(micro-O)(phen)4(H2O)2]4+ (1) (Fig. 1, phen = 1,10-phenanthroline) equilibrates with [Fe2(micro-O)(phen)4(H2O)(OH)]3+ (2) and [Fe2(micro-O)(phen)4(OH)2]2+ (3) in aqueous solution in the presence of excess phen, where no phen-releasing equilibria from 1, 2 and 3 exist. 1 quantitatively oxidizes ascorbic acid (H2A) to dehydroascorbic acid (A) in the pH range 3.00-5.50 in the presence of exces...

The stimulatory effect of ferrous salts on the peroxidation of phospholipids can be enhanced by EDTA when the concentration of Fe2+ in the reaction is greater than that of EDTA. Hydroxyl-radical scavengers do not inhibit peroxidation until the concentrations of Fe2+ and EDTA in the reaction are equal. Lipid peroxidation is then substantially initiated by hydroxyl radicals derived from a Fenton-...

Bleomycin (BLM) is an anticancer antibiotic isolated from the supernatant of Streptomyces verticillus culture [21]. The cytotoxic activity of BLM depends on generation of singleand double-strand breaks in DNA (for review, see [16]). Indispensable for this BLM activity is the presence of metal ions, specifically Fe2+. Fe2+ BLM complexed with O2 or Fe 3+ BLM complexed with H2O2 leads to formation...

Nano-particles of polycrystalline Zn Fe2 O4 are prepared using sol-gel method with Ni, and Sm. They are obtained as dried gel after the successful chemical reaction of their respective metal nitrate solutions in the midst of citric acid as catalyst. Synthesis of materials is confirmed using XRD from the report of single phase polycrystalline ferrite material. The magnetic properties of Zn-ferri...

The adsorption of Fe2+ by the manganese oxide coated zeolite (MOCZ) and iron oxide coated zeolite (FOCZ) was studied. Surface properties of adsorbents have been investigated for monitoring their changes and morphology for both of the MOCZ and FOCZ. Main variables namely; contact time, pH, initial concentration of Fe2+, size and dosage of adsorbent have been optimized, and the results contrasted...

The mechanism of the fluorescence quenching of aqueous thionine by various metal ions (Ce3+_, Fe2+, Mn2+, Mg2+, Cs+ and Na+) was studied at pn = 2.5. The following Stern-Volmer constants (K s v) were determined: XSv(Fe2+) == 1.13 dm3 mol -1 , Ksw(Mn2+) = 0.24 dm3 mol"1, Ksv(Ce3+) = 0.24 dm3 mol -1, i£sv(Cs~) — 0.03 dm3 mol -1 . At concentrations below 1 mol.dm -3 Na2S04 and MgS04 are very weak ...

Protein-bound iron-sulfur clusters and their synthetic analogues are characterized by tetrahedral metal sites, multiple oxidation levels, and exchange coupling. The recent attainment of several all-ferrous protein clusters and the presence of sulfide- and thiolate-bridged sites in the all-ferrous state of the nitrogenase P-cluster provides an imperative for determination of exchange coupling be...