نتایج جستجو برای: fecal calprotectin

تعداد نتایج: 26991  

2016
Peter C Ambe Valerie Orth Daniel Gödde Hubert Zirngibl

BACKGROUND Is the patient really suffering from acute appendicitis? Right lower quadrant pain is the most common sign of acute appendicitis. However, many other bowels pathologies might mimic acute appendicitis. Due to fear of the consequences of delayed or missed diagnosis, the indication for emergency appendectomy is liberally made. This has been shown to be associated with high rates of nega...

2016
Suzanna Attia Christian J Versloot Wieger Voskuijl Sara J van Vliet Valeria Di Giovanni Ling Zhang Susan Richardson Céline Bourdon Mihai G Netea James A Berkley Patrick F van Rheenen Robert Hj Bandsma

BACKGROUND Diarrhea affects a large proportion of children with severe acute malnutrition (SAM). However, its etiology and clinical consequences remain unclear. OBJECTIVE We investigated diarrhea, enteropathogens, and systemic and intestinal inflammation for their interrelation and their associations with mortality in children with SAM. DESIGN Intestinal pathogens (n = 15), cytokines (n = 2...

2017
Pieter F de Groot Clara Belzer Ömrüm Aydin Evgeni Levin Johannes H Levels Steven Aalvink Fransje Boot Frits Holleman Daniël H van Raalte Torsten P Scheithauer Suat Simsek Frank G Schaap Steven W M Olde Damink Bart O Roep Joost B Hoekstra Willem M de Vos Max Nieuwdorp

OBJECTIVE Environmental factors driving the development of type 1 diabetes (T1D) are still largely unknown. Both animal and human studies have shown an association between altered fecal microbiota composition, impaired production of short-chain fatty acids (SCFA) and T1D onset. However, observational evidence on SCFA and fecal and oral microbiota in adults with longstanding T1D vs healthy contr...

2016
Ying Zhuge Qiu-Ping Huang Qing Li Jun-Shan Wang

Aims We aimed to perform a meta-analysis of the predictive capacity of fecal calprotectin (FC) in activity and relapse of Crohn's disease (CD). Materials and methods MEDLINE, EMBASE, and the Cochrane Library databases were searched systematically. Pooled sensitivity, specificity, and other diagnostic indices were evaluated. Results A total of 1,252 CD patients from 18 different studies were...

2016
Seema Rajani Hien Q. Huynh Leanne Shirton Cheryl Kluthe Donald Spady Connie Prosser Jon Meddings Gwen R. Rempel Rabindranath Persad Justine M. Turner

Background. The European Society for Pediatric Gastroenterology, Hepatology and Nutrition endorses serological diagnosis (SD) for pediatric celiac disease (CD). The objective of this study was to pilot SD and to prospectively evaluate gastrointestinal permeability and mucosal inflammation at diagnosis and after one year on the gluten-free diet (GFD). We hypothesized that SD would be associated ...

Journal: :Acta biochimica Polonica 2014
Elzbieta Czub Jan K Nowak Anna Szaflarska-Poplawska Urszula Grzybowska-Chlebowczyk Piotr Landowski Jerzy Moczko Daria Adamczak Przemyslaw Mankowski Tomasz Banasiewicz Andrzej Plawski Jaroslaw Walkowiak

AIMS Accurate assessment of inflammatory bowel disease (IBD) activity is the cornerstone of effective therapy. Fecal M2 isoform of pyruvate kinase (M2-PK) and fecal calprotectin (FC) are noninvasive markers of mucosal inflammation in IBD. The aim of this study was to compare performance of M2-PK and FC in assessment of pediatric ulcerative colitis (UC) and Crohn's disease (CD) severity and acti...

2016
Hengameh C. Mirsepasi-Lauridsen Sofie Ingdam Halkjaer Esben Munk Mortensen Magnus C. Lydolph Inge Nordgaard-Lassen Karen Angeliki Krogfelt Andreas Munk Petersen

E. coli of the phylogenetic group B2 harbouring Extra intestinal Pathogenic Escherichia coli (ExPEC) genes are frequently seen as colonizers of the intestine in patients with active ulcerative colitis (UC). In this study, we describe the influence of E. coli Nissle (EcN) B2 as add-on treatment to conventional therapies in patients with active UC. For this study one hundred active UC patients we...

Journal: :Annals of hepatology 2016
Kirsten E Pijls Daisy M A E Jonkers Montserrat Elizalde Marie-Jose Drittij-Reijnders Guido R Haenen Aalt Bast Ad A M Masclee Ger H Koek

BACKGROUND Liver cirrhosis is associated with intestinal epithelial barrier dysfunction, which may be affected by oxidative stress. Studies in cirrhotic rats provided evidence for intestinal oxidative stress, but studies in cirrhotic patients are scarce. We have shown intestinal barrier dysfunction in patients with compensated cirrhosis. AIM The present study aimed to investigate whether oxid...

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