نتایج جستجو برای: feeder free condition

تعداد نتایج: 816016  

2015
Yi-Ling Chen Shiun Chang Ting-Ting Chen Chien-Kuo Lee R. Keith Reeves

Dendritic cells (DCs), including conventional DCs (cDCs) and plasmacytoid DCs (pDCs) are critical for initiating and controlling the immune response. However, study of DC, particularly pDC, function is hampered by their low frequency in lymphoid organs, and existing methods for in vitro DC generation preferentially favor the production of cDCs over pDCs. Here, we demonstrated that pDCs could be...

2014
Yu Zhang Chao Wei Pengfei Zhang Xia Li Tong Liu Yong Pu Yunsheng Li Zubing Cao Hongguo Cao Ya Liu Xiaorong Zhang Yunhai Zhang

Induced pluripotent stem cells (iPSCs) are somatic cells reprogrammed by ectopic expression of transcription factors or small molecule treatment, which resemble embryonic stem cells (ESCs). They hold great promise for improving the generation of genetically modified large animals. However, few porcine iPSCs (piPSCs) lines obtained currently can support development of cloned embryos. Here, we ge...

Journal: :The Journal of veterinary medical science 2012
Sasithorn Panasophonkul Theerawat Tharasanit Mongkol Techakumphu

In the present study, the effect of two types of allogeneic-derived feeder cells [porcine ear and tail skin fibroblasts (PESF, PTSF)] and three types of xenogeneic-derived feeder cells [human foreskin fibroblasts (HFK), mouse embryonic fibroblasts (MEF) and immortalized mouse embryonic fibroblasts (STO)] on the isolation and cultivation of putative porcine embryonic stem cells (pESCs) was evalu...

Journal: :iranian biomedical journal 0
سعید رجبعلیان saeed rajabalian زهرا صمدی بهرامی zahra samadi bahrami وحیده فراهت vahideh farahat فاضل شکری fazel shokri

human diploid fibroblast cells produce a spectrum of necessary growth factors and extracellular matrix (ecm) components essential for growth and proliferation of a variety of other cell types. in this study, the effect of five human embryonic fibroblast cell lines, isolated from liver, lung, skin and foreskin tissues, was investigated. a coculture system analyse was employed to cloning efficien...

Journal: :PLoS ONE 2008
Annette Schneider Dimitry Spitkovsky Peter Riess Marek Molcanyi Naidu Kamisetti Marc Maegele Jürgen Hescheler Ute Schaefer

A variety of embryonic and adult stem cell lines require an initial co-culturing with feeder cells for non-differentiated growth, self renewal and maintenance of pluripotency. However for many downstream ES cell applications the feeder cells have to be considered contaminations that might interfere not just with the analysis of experimental data but also with clinical application and tissue eng...

پایان نامه :دانشگاه بین المللی امام خمینی (ره) - قزوین - دانشکده علوم پایه 1390

چکیده : * در یک واکنش تک ظرفی و با استفاده از واکنش آلدهید های آروماتیک و 3- متیل 1- فنیل پیرازولین-5- ان با نسبت مولی 1:1، ساختارهای هتروسیکل پیرازول سنتز شد. از مزایای آن، انجام واکنش در دمای اتاق، عدم نیاز به کاتالیزور، بازده بالای واکنش، استفاده از آب بعنوان حلال سبز و بی خطر به جای حلال های آلی وسمی می باشد . * توانستیم با استفاده از ملدرام اسید ومشتقات 2- هیدروکسی بنزآلدهید، ترکی...

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