Free radical scavenging and cell aggregation inhibitory activities of 36 secondary metabolites isolated from the methanolic extracts of Verbascum cilicicum Boiss., V. lasianthum Boiss. ex Bentham, V pterocalycinum var. mutense Hub.-Mor., and V. salviifolium Boiss. (Scrophulariaceae) were investigated. The isolated compounds, 6-O-vaniloyl ajugol (1), ilwensisaponin A (2), ilwensisaponin C (3), v...

BACKGROUND Since ancient times, various infectious diseases have been treated using herbal drugs. Today, efforts regarding the discovery of the effectual components of plants possessing antimicrobial properties are advanced. Herbal essential oils are widely used for treatment of various diseases, and they play an important role in health care considerations. METHODS The antibacterial activity...

BACKGROUND The Candida species are the most important factors of fungal infections in humans and animals. It is necessary to prepare antifungal or antimicrobial drugs because of increasing drug resistance. The natural treatment of diseases of bacterial origin using medicinal plants is important. In this study the effect of antimicrobial medicinal herbal essential oils and conventional antifunga...

The clinical use of anthracycline Doxorubicin as an antineoplastic drug in cancer therapy is limited by cardiotoxic effects that can lead to congestive heart failure. Recent studies have shown several promising activities different species the genus Ferula belonging Apiaceae Family. communis main source Ferutinin—a bioactive compound isolated from many Ferula—studied both vitro and vivo because...

This study was conducted to investigate the effect of ecological factors on distribution, presence and absence of species Ferula ovina and F. persica in the semi-arid rangelands of Zanjan province, Iran in 2015. The locations of ten 4m2 plots with 15m spacing on three 150 m long transects were systematically randomized and determined in each key area within each hab...

The fruiting branches of Colutea cilicica Boiss. & Bal., along with leaves and fruits, have been used to heal inflammatory wounds at traditional medicine in various parts of Turkey. In order to evaluate the wound healing activity of the plant, aqueous extracts were prepared from the flowering parts and fruits of Colutea cilicica Boiss. & Bal. by using 40°C distilled water. Incision wound healin...

Resistance to chemotherapy and recurrence are major hurdles treating hormone receptor-negative breast cancer. The crude extract natural products obtained from medicinal plants believed be multitargeted possess less toxicity as compared synthetic compounds. aerial parts roots of Moricandia sinaica (Boiss.) Boiss were used prepare the extracts in solvents different polarities. Human cancer cell l...

BACKGROUND Premenstrual Syndrome (PMS) is a common problem in women. Zataria multiflora Boiss is a valuable plant. This herbal plant has been used in different conditions. OBJECTIVES The study was performed to investigate the effects of Zataria multiflora Boiss to control PMS symptoms. MATERIALS AND METHODS This study was a double-blinded, prospective randomized trial. The study population ...