BACKGROUND Continuous 12-lead ECG monitoring (Holter) in early-phase pharmaceutical studies is today widely used as an ideal platform to extract discrete ECGs for analysis. The extraction process is typically performed manually by trained readers using commercial Holter processing systems. METHODS Antares, a novel method for automatic 12-lead extraction from continuous Holter recordings apply...

This work describes a Radial Basis Function (RBF) neural network method used to analyze ECG signals for diagnosing cardiac arrhythmias effectively. The proposed method can accurately classify and differentiate normal (Normal) and abnormal heartbeats. Abnormal heartbeats include left bundle branch block (LBBB), right bundle branch block (RBBB), atrial premature contractions (APC) and premature v...

In this study we present a noninvasive method that enables the investigation of the fetal heart rate (FHR) fluctuations. The objective was to design a quantitative measurement to assess the fetal autonomic nervous system and to investigate its development as a function of the gestational age. Our Medical Physics group has developed a complex algorithm for online beat-to-beat detection of the fe...

This paper evaluates the performance of some major ICA algorithms like Cardoso’s Joint Approximate Diagonalization of Eigen matrices (JADE), Bell and Sejnowski’s Infomax algorithm and Comon’s algorithm in a biomedical blind source separation problem. Independent signals representing Fetal ECG (FECG) and Maternal ECG (MECG) generated and then mixed linearly to simulate a recording of electrocard...

Electrocardiogram (ECG) and magnetocardiogram (MCG) signals are among the most considerable sources of noise for other biomedical signals. In some recent works, a Bayesian filtering framework has been proposed for denoising the ECG signals. In this paper, it is shown that this framework may be effectively used for removing cardiac contaminants such as the ECG, MCG and ballistocardiographic arti...

The fetal heart rate (FHR) is a useful tool in the assessment of the condition of the fetal before and during labour. Fetal Electrocardiography (FECG) (Sureau, 1996) uses noninvasive surface electrodes placed on the maternal abdomen is another tool for FHR recording (Sureau, 1996). The fetal signal is weak relative to the maternal signal and to the competing noise. Widrow et al. (Widrow et al.,...

Now telemedicine is producing a great impact for health care of the patients, especially who are located in the remote nonclinical environments. This paper presents a research work that concerns to implement simple customized and portable emergency medical care information for Fetal Electro Electrocardiography (FECG) monitoring system. The research work is included both the hardware and softwar...

The paper present a various techniques that enables the investigations of the fetal heart rate (FHR) fluctuations. Later, the common problems associated with these techniques are discussed with some solutions. A non-invasive technique is also proposed for fetal ECG monitoring. The proposed system will be designed to measure the fetal heart rate variability for the evaluation of autonomic nervou...

In this paper, we propose a novel blind-source separation method to extract fetal ECG from a single-channel signal measured on the abdomen of the mother. The signal is a mixture of the fetal ECG, the maternal ECG and noise. The key idea is to project the signal into higher dimensions, and then use an assumption of statistical independence between the components to separate them from the mixture...

Electrocardiogram (ECG) is a graphic recording of the electrical activity produced by the heart. The accuracy of any electrocardiogram waveform extraction plays a vital role in helping a better diagnosis of any heart related illnesses. We present a computer-aided application model for detection of cardiac arrhythmia in ECG signal, which consists of signal pre-processing and detection of the ECG...